摘要

In this paper we have simulated an in vitro lung cancer microenvironment by dielectrophoresis (DEP) patterning. Heterogeneous cells were patterned on the glass substrate, above which a microfluidic gradient is integrated to generate different concentration of target therapy drug (Iressa). Taking advantage of DEP pattern and microfluidic gradient, we designed a biochip to mimic the in vivo conditions. The influence of drug treatment for cell patterning is better than the non-patterned case as visualized in cell viability rate by MTT assay.

原文英語
主出版物標題2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
發行者Institute of Electrical and Electronics Engineers Inc.
頁面646-649
頁數4
ISBN(列印)9781479989553
DOIs
出版狀態已發佈 - 8月 5 2015
事件18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, 美国
持續時間: 6月 21 20156月 25 2015

其他

其他18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
國家/地區美国
城市Anchorage
期間6/21/156/25/15

ASJC Scopus subject areas

  • 儀器
  • 電氣與電子工程

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