摘要
In this paper we have simulated an in vitro lung cancer microenvironment by dielectrophoresis (DEP) patterning. Heterogeneous cells were patterned on the glass substrate, above which a microfluidic gradient is integrated to generate different concentration of target therapy drug (Iressa). Taking advantage of DEP pattern and microfluidic gradient, we designed a biochip to mimic the in vivo conditions. The influence of drug treatment for cell patterning is better than the non-patterned case as visualized in cell viability rate by MTT assay.
原文 | 英語 |
---|---|
主出版物標題 | 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 |
發行者 | Institute of Electrical and Electronics Engineers Inc. |
頁面 | 646-649 |
頁數 | 4 |
ISBN(列印) | 9781479989553 |
DOIs | |
出版狀態 | 已發佈 - 8月 5 2015 |
事件 | 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, 美国 持續時間: 6月 21 2015 → 6月 25 2015 |
其他
其他 | 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 |
---|---|
國家/地區 | 美国 |
城市 | Anchorage |
期間 | 6/21/15 → 6/25/15 |
ASJC Scopus subject areas
- 儀器
- 電氣與電子工程