Leukoencephalopathy after inhalation of heroin vapor

Yeu Jhy Chang, Chon Haw Tsai, Chi Jen Chen

研究成果: 雜誌貢獻文章同行評審

17 引文 斯高帕斯(Scopus)


A 25-year-old man presented in March 1996 with progressive dysarthria, cerebellar ataxia, and dystonia, which began after he inhaled heroin vapor for a full day 2 months previously. The patient had a 2-year history of heroin inhalation. Magnetic brain stimulation showed waveform dysynchronization suggestive of motor pathway perturbation above the cervical spinal level. Brain computed tomography and magnetic resonance imaging revealed extensive symmetric white matter involvement of bilateral cerebral and cerebellar hemispheres and the brainstem, especially along the corticospinal tract. The clinical features, electrophysiologic manifestations, and imaging studies strongly indicated a lipophilic toxin-induced demyelinating process, mainly involving the central motor system, as the most likely cause of heroin leukoencephalopathy. This is the first reported case of heroin-related leukoencephalopathy in Taiwan.

頁(從 - 到)758-760
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
出版狀態已發佈 - 9月 1997

ASJC Scopus subject areas

  • 醫藥 (全部)


深入研究「Leukoencephalopathy after inhalation of heroin vapor」主題。共同形成了獨特的指紋。