Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

Chia-Kwung Fan; Yun-Ho Lin; Chien Ching Hung; Kua-Eyre Su

Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

貢獻的翻譯標題: 長期培養之犬蛔蟲受孕卵內幼蟲於小鼠的移行行為

Chia-Kwung Fan, Yun-Ho Lin, Chien Ching Hung, Kua-Eyre Su

研究成果: 雜誌貢獻 › 文章 › 同行評審

摘要

藉幼蟲回收研究評估儲存於2%福馬林液內，於4℃下保存14個月之犬蛔蟲受孕卵感染小鼠第一天至第四百六十九天後，幼蟲於小鼠體內的移行行為。每次犧牲三隻感染鼠與二隻同齡未感染鼠，對肝臟和肺臟（肝肺期）與肌肉和腦部（神經肌肉期）組纖以酸性的胃蛋白酵素進行消化。自肝肺期的幼蟲回收於感染後第五天達到最高，而非感染後的第二天，此後，大部分的幼蟲轉為移行至神經肌肉期。就統計學而言，肝肺期與神經肌肉期的幼蟲回收與時間分別成負與正相關（r = - 0.688，P = 0.005；r = 0.138，P = 0.327）。綜合而言，儘管14個月培養的犬蛔蟲幼蟲似乎延遲移行至肝肺期，大部分仍出現於神經肌肉期，特別是腦部。

貢獻的翻譯標題	長期培養之犬蛔蟲受孕卵內幼蟲於小鼠的移行行為
原文	英語
頁（從 - 到）	99-105
頁數	7
期刊	臺灣獸醫學雜誌
卷	30
發行號	2
出版狀態	已發佈 - 2004

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http://www.AiritiLibrary.com/Publication/Index/16826485-200406-201209030020-201209030020-99-105

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@article{706fe1b5a4b742b9855595fa9a7cd3c7,

title = "Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice",

abstract = "Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2% formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.",

keywords = "犬蛔蟲, 幼蟲移行行為, 小鼠, Larval migratory behavior, Mice, Toxocara canis",

author = "Chia-Kwung Fan and Yun-Ho Lin and Hung, {Chien Ching} and Kua-Eyre Su",

year = "2004",

language = "English",

volume = "30",

pages = "99--105",

journal = "臺灣獸醫學雜誌",

issn = "1682-6485",

publisher = "中華民國獸醫學會",

number = "2",

}

TY - JOUR

T1 - Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

AU - Fan, Chia-Kwung

AU - Lin, Yun-Ho

AU - Hung, Chien Ching

AU - Su, Kua-Eyre

PY - 2004

Y1 - 2004

N2 - Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2% formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.

AB - Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2% formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.

KW - 犬蛔蟲

KW - 幼蟲移行行為

KW - 小鼠

KW - Larval migratory behavior

KW - Mice

KW - Toxocara canis

M3 - Article

SN - 1682-6485

VL - 30

SP - 99

EP - 105

JO - 臺灣獸醫學雜誌

JF - 臺灣獸醫學雜誌

IS - 2

ER -

Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

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