摘要
Chemical investigation of the bark of Calocedrus macrolepis var. formosana, an endemic tree in Taiwan, has led to the isolation of a novel terpenoid 1. Compound 1 with a rare C35 skeleton constructed by a diterpene and a sesquiterpene moieties. Its structure was elucidated by spectroscopic interpretations. The anti-proliferation activity of 1 against human oral epidermoid carcinoma KB cells was evaluated, and the IC50 value was determined to be 9.2 ± 0.4 μM.
原文 | 英語 |
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頁(從 - 到) | 515-517 |
頁數 | 3 |
期刊 | Tetrahedron Letters |
卷 | 52 |
發行號 | 4 |
DOIs | |
出版狀態 | 已發佈 - 1月 26 2011 |
ASJC Scopus subject areas
- 生物化學
- 有機化學
- 藥物發現