Labdane diterpenoid glycosides from Alpinia densespicata and their nitric oxide inhibitory activities in macrophages

Yu Jen Kuo; Ping Chun Hsiao; Li Jie Zhang; Ming Der Wu; Yu Han Liang; Hsiu O. Ho; Yao Haur Kuo

doi:10.1021/np900019n

Labdane diterpenoid glycosides from Alpinia densespicata and their nitric oxide inhibitory activities in macrophages

Yu Jen Kuo, Ping Chun Hsiao, Li Jie Zhang, Ming Der Wu, Yu Han Liang, Hsiu O. Ho, Yao Haur Kuo

研究成果: 雜誌貢獻 › 文章 › 同行評審

17 引文斯高帕斯（Scopus）

摘要

Four new labdane diterpene glycosides (1-4) named alpindenosides A, B, C, and D, two new norditerpene glycosides (5, 6) named noralpindenosides A and B, and three known flavonoid glycosides (7-9) have been isolated from the stems of Alpinia densespicata. Structural elucidation of compounds 1-6 was based on spectroscopic data. Compounds 1-9 all exhibited moderate NO inhibitory activities, whereas they were noncytotoxic at 20 μ M against several human tumor cell lines.

原文	英語
頁（從 - 到）	1097-1101
頁數	5
期刊	Journal of Natural Products
卷	72
發行號	6
DOIs	https://doi.org/10.1021/np900019n
出版狀態	已發佈 - 6月 26 2009

ASJC Scopus subject areas

藥物發現
分析化學
分子醫學
補充和替代醫學
藥理
藥學科學
有機化學

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10.1021/np900019n

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abstract = "Four new labdane diterpene glycosides (1-4) named alpindenosides A, B, C, and D, two new norditerpene glycosides (5, 6) named noralpindenosides A and B, and three known flavonoid glycosides (7-9) have been isolated from the stems of Alpinia densespicata. Structural elucidation of compounds 1-6 was based on spectroscopic data. Compounds 1-9 all exhibited moderate NO inhibitory activities, whereas they were noncytotoxic at 20 μ M against several human tumor cell lines.",

author = "Kuo, {Yu Jen} and Hsiao, {Ping Chun} and Zhang, {Li Jie} and Wu, {Ming Der} and Liang, {Yu Han} and Ho, {Hsiu O.} and Kuo, {Yao Haur}",

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AU - Kuo, Yu Jen

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AU - Wu, Ming Der

AU - Liang, Yu Han

AU - Ho, Hsiu O.

AU - Kuo, Yao Haur

PY - 2009/6/26

Y1 - 2009/6/26

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Labdane diterpenoid glycosides from Alpinia densespicata and their nitric oxide inhibitory activities in macrophages

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