Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013)

Hsueh Yun Lee; Chia-Ron Yang; Mei-Jung Lai; Han-Li Huang; Yi-Ling Hsieh; Yi-Min Liu; Teng-Kuang Yeh; Yu-Hsuan Li; Samir Mehndiratta; Che-Ming Teng; Jing Ping Liou

doi:10.1002/cbic.201390034

Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013)

Hsueh Yun Lee, Chia-Ron Yang, Mei-Jung Lai, Han-Li Huang, Yi-Ling Hsieh, Yi-Min Liu, Teng-Kuang Yeh, Yu-Hsuan Li, Samir Mehndiratta, Che-Ming Teng, Jing Ping Liou

研究成果: 雜誌貢獻 › 文章 › 同行評審

摘要

The inside cover picture shows a SAR study of synthetic N-hydroxyacrylamides, described by J.-P. Liou et al. on p. 1248 ff., that identified 3-[1- (4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]-N-hydroxyacrylamide as a potent HDAC inhibitor. This compound not only suppresses the production of lipopolysaccharide-induced cytokines but also markedly reduces carrageenan-induced inflammation in rat. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

原文	英語
頁（從 - 到）	1150
頁數	1
期刊	ChemBioChem
卷	14
發行號	10
DOIs	https://doi.org/10.1002/cbic.201390034
出版狀態	已發佈 - 7月 2013

Keywords

Anti-inflammatory agents
Gene expression
Histone deacetylase
Indolines
Inhibitors

ASJC Scopus subject areas

生物化學
有機化學
分子醫學
分子生物學

存取文件

10.1002/cbic.201390034

其它文件與鏈接

引用此

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title = "Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013)",

abstract = "The inside cover picture shows a SAR study of synthetic N-hydroxyacrylamides, described by J.-P. Liou et al. on p. 1248 ff., that identified 3-[1- (4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]-N-hydroxyacrylamide as a potent HDAC inhibitor. This compound not only suppresses the production of lipopolysaccharide-induced cytokines but also markedly reduces carrageenan-induced inflammation in rat.",

keywords = "Anti-inflammatory agents, Gene expression, Histone deacetylase, Indolines, Inhibitors, Anti-inflammatory agents, Gene expression, Histone deacetylase, Indolines, Inhibitors",

author = "Lee, {Hsueh Yun} and Chia-Ron Yang and Mei-Jung Lai and Han-Li Huang and Yi-Ling Hsieh and Yi-Min Liu and Teng-Kuang Yeh and Yu-Hsuan Li and Samir Mehndiratta and Che-Ming Teng and Liou, {Jing Ping}",

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AU - Lee, Hsueh Yun

AU - Yang, Chia-Ron

AU - Lai, Mei-Jung

AU - Huang, Han-Li

AU - Hsieh, Yi-Ling

AU - Liu, Yi-Min

AU - Yeh, Teng-Kuang

AU - Li, Yu-Hsuan

AU - Mehndiratta, Samir

AU - Teng, Che-Ming

AU - Liou, Jing Ping

PY - 2013/7

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AB - The inside cover picture shows a SAR study of synthetic N-hydroxyacrylamides, described by J.-P. Liou et al. on p. 1248 ff., that identified 3-[1- (4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]-N-hydroxyacrylamide as a potent HDAC inhibitor. This compound not only suppresses the production of lipopolysaccharide-induced cytokines but also markedly reduces carrageenan-induced inflammation in rat.

KW - Anti-inflammatory agents

KW - Gene expression

KW - Histone deacetylase

KW - Indolines

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KW - Anti-inflammatory agents

KW - Gene expression

KW - Histone deacetylase

KW - Indolines

KW - Inhibitors

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Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013)

摘要

Keywords

ASJC Scopus subject areas

存取文件

其它文件與鏈接

指紋

引用此