Inhibition of cyclic strain-induced endothelin-1 secretion by baicalein in human umbilical vein endothelial cells

Agriculture & Biology

• human umbilical vein endothelial cells 97%
• endothelins 85%
• secretion 47%
• mitogen-activated protein kinase 29%
• endothelial cells 27%
• reactive oxygen species 22%
• Oriental traditional medicine 21%
• Scutellaria baicalensis 20%
• antioxidants 17%
• plant vascular system 17%
• stroke 15%
• reporter genes 13%
• phosphorylation 11%
• bioactive properties 11%
• medicinal plants 11%
• cell culture 10%
• flavonoids 10%
• gene expression 8%
• assays 7%
• testing 5%
• proteins 4%

Medicine & Life Sciences

• baicalein 98%
• Endothelin-1 72%
• Human Umbilical Vein Endothelial Cells 71%
• Extracellular Signal-Regulated MAP Kinases 18%
• Reactive Oxygen Species 13%
• East Asian Traditional Medicine 12%
• Antioxidants 12%
• Endothelial Cells 12%
• Scutellaria baicalensis 12%
• 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 11%
• Transcription Factor AP-1 9%
• Medicinal Plants 9%
• Flavonoids 8%
• Reporter Genes 8%
• Phosphorylation 5%
• Stroke 5%
• Gene Expression 5%
• Blood Vessels 4%

Chemical Compounds

• Endothelin-1 100%
• Baicalein 100%
• Reactive Oxygen Metabolite 15%
• Antioxidant Agent 12%
• Trolox 10%
• Flavonoid 8%
• Bioactivity 6%