TY - JOUR
T1 - Increased risk of prostate cancer following sexually transmitted infection in an Asian population
AU - Chung, S. D.
AU - Lin, Yen-Kuang
AU - Huang, C. C.
AU - Lin, H. C.
PY - 2013/12
Y1 - 2013/12
N2 - The relationship between sexually transmitted infections (STIs) and prostate cancer (PC) remains inconclusive. Moreover, all such studies to date have been conducted in Western populations. This study aimed to investigate the risk of PC following STI using a population-based matched-cohort design in Taiwan. The study cohort comprised 1055 patients with STIs, and 10Â 550 randomly selected subjects were used as a comparison cohort. Cox proportional hazards regression analysis revealed that the hazard ratio for PC during the 5-year follow-up period for patients with a STI was 1·95 (95% confidence interval 1·18-3·23), that of comparison subjects after adjusting for urbanization level, geographical region, monthly income, hypertension, diabetes, hyperlipidaemia, obesity, chronic prostatitis, history of vasectomy, tobacco use disorder, and alcohol abuse. We concluded that the risk of PC was higher for men who were diagnosed with a STI in an Asian population.
AB - The relationship between sexually transmitted infections (STIs) and prostate cancer (PC) remains inconclusive. Moreover, all such studies to date have been conducted in Western populations. This study aimed to investigate the risk of PC following STI using a population-based matched-cohort design in Taiwan. The study cohort comprised 1055 patients with STIs, and 10Â 550 randomly selected subjects were used as a comparison cohort. Cox proportional hazards regression analysis revealed that the hazard ratio for PC during the 5-year follow-up period for patients with a STI was 1·95 (95% confidence interval 1·18-3·23), that of comparison subjects after adjusting for urbanization level, geographical region, monthly income, hypertension, diabetes, hyperlipidaemia, obesity, chronic prostatitis, history of vasectomy, tobacco use disorder, and alcohol abuse. We concluded that the risk of PC was higher for men who were diagnosed with a STI in an Asian population.
KW - Prostate cancer
KW - sexually transmitted infections
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U2 - 10.1017/S0950268813000459
DO - 10.1017/S0950268813000459
M3 - Article
C2 - 23461984
AN - SCOPUS:84893106142
SN - 0950-2688
VL - 141
SP - 2663
EP - 2670
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 12
ER -