Increased prevalences of head and neck cancers in patients with Sjögren's syndrome

Tzong Hann Yang, Yen Fu Cheng, Chin Shyan Chen, Herng Ching Lin

研究成果: 雜誌貢獻文章同行評審

摘要

Objective: This study aimed to investigate prevalences of head and neck cancers in patients with and those without Sjögren's syndrome using a population-based dataset. Methods: We retrieved sampled patients from Taiwan's Longitudinal Health Insurance Database. This study included 38 930 patients with Sjögren's syndrome and 155 720 propensity-score matched comparison patients without Sjögren's syndrome. Results: Chi-squared tests revealed that there was a statistically significant difference in the prevalences of head and neck cancers between patients with Sjögren's syndrome and comparison patients (1.77% vs. 1.22%, p < 0.001). The odds ratio for head and neck cancers for patients with Sjögren's syndrome relative to the comparison group was 1.452 (95% CI = 1.325–1.592). Conclusions: Our study demonstrated that patients with Sjögren's syndrome face increased odds of head and neck cancers, encompassing several sites including the oral cavity, oropharynx, nasopharynx, and thyroid.

原文英語
頁(從 - 到)2874-2881
頁數8
期刊Head and Neck
45
發行號11
DOIs
出版狀態已發佈 - 11月 2023

ASJC Scopus subject areas

  • 耳鼻咽喉科

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