In vivo graft performance of an improved bone substitute composed of poor crystalline hydroxyapatite based biphasic calcium phosphate

Ching Lien Hung; Jen Chang Yang; Wei Jen Chang; Chih Yuan Hu; Yong Ho Lin; Chun Hsien Huang; Chien Chung Chen; Sheng Yang Lee; Nai Chia Teng

doi:10.4012/dmj.2010-060

In vivo graft performance of an improved bone substitute composed of poor crystalline hydroxyapatite based biphasic calcium phosphate

Ching Lien Hung
, Jen Chang Yang
, Wei Jen Chang
, Chih Yuan Hu
, Yong Ho Lin
, Chun Hsien Huang
, Chien Chung Chen
, Sheng Yang Lee
, Nai Chia Teng

研究成果: 雜誌貢獻 › 文章 › 同行評審

15 引文斯高帕斯（Scopus）

摘要

The ability to promote new bone formation of poor crystalline hydroxyapatite (PC-HA) based biphasic calcium phosphate (BCP) bone substitutes were investigated. Various ratios of porous PC-HA/β-TCP (70/30, 60/40, and 0/100) grafts were fabricated. SEM and XRD measurements were performed to study the morphology and crystalline structure. Cylindrical artificial bone defects (3×6 mm2) were produced in alveolar bone at premolars extraction site and then filled with sterilized bone grafts. Commercial MBCP® and unfilled empty defect served as control groups. At 8 weeks postoperation, samples were harvested from each artificial defect site for histological analysis. New bone formation of all the PC-HA/β-TCP groups was significantly greater than that of the empty control group (p

原文	英語
頁（從 - 到）	21-28
頁數	8
期刊	Dental Materials Journal
卷	30
發行號	1
DOIs	https://doi.org/10.4012/dmj.2010-060
出版狀態	已發佈 - 2011

ASJC Scopus subject areas

陶瓷和複合材料
一般牙醫學

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10.4012/dmj.2010-060

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title = "In vivo graft performance of an improved bone substitute composed of poor crystalline hydroxyapatite based biphasic calcium phosphate",

abstract = "The ability to promote new bone formation of poor crystalline hydroxyapatite (PC-HA) based biphasic calcium phosphate (BCP) bone substitutes were investigated. Various ratios of porous PC-HA/β-TCP (70/30, 60/40, and 0/100) grafts were fabricated. SEM and XRD measurements were performed to study the morphology and crystalline structure. Cylindrical artificial bone defects (3×6 mm2) were produced in alveolar bone at premolars extraction site and then filled with sterilized bone grafts. Commercial MBCP{\textregistered} and unfilled empty defect served as control groups. At 8 weeks postoperation, samples were harvested from each artificial defect site for histological analysis. New bone formation of all the PC-HA/β-TCP groups was significantly greater than that of the empty control group (p",

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AU - Hung, Ching Lien

AU - Yang, Jen Chang

AU - Chang, Wei Jen

AU - Hu, Chih Yuan

AU - Lin, Yong Ho

AU - Huang, Chun Hsien

AU - Chen, Chien Chung

AU - Lee, Sheng Yang

AU - Teng, Nai Chia

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KW - Biphasic calcium phosphate

KW - Bone graft

KW - Hydroxyapatite

KW - In vivo

KW - β-tricalcium phosphate

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In vivo graft performance of an improved bone substitute composed of poor crystalline hydroxyapatite based biphasic calcium phosphate

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