In situ detection of Epstein-Barr virus in breast cancer

Jan Show Chu, Chung Chung Chen, King Jen Chang

研究成果: 雜誌貢獻文章同行評審

62 引文 斯高帕斯(Scopus)

摘要

Epstein-Barr virus (EBV) is strongly associated with nasopharyngeal carcinoma and some lymphoepithelioma-like carcinomas from other anatomic sites. This study investigates the presence of EBV in breast cancer. Immunohistochemistry for EBV proteins (EBV nuclear antigen-2 and latent membrane protein-1) and in situ hybridization for EBV-encoded small nuclear RNAs (EBER-1 and -2) were performed in 60 invasive breast cancers. None of the 60 breast cancer samples showed detectable EBV. These results suggest that EBV may not play a significant role in the etiology of breast cancers in Taiwan.

原文英語
頁(從 - 到)53-57
頁數5
期刊Cancer Letters
124
發行號1
DOIs
出版狀態已發佈 - 2月 13 1998
對外發佈

ASJC Scopus subject areas

  • 癌症研究
  • 分子生物學
  • 腫瘤科

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