Three new prenylated C6-C3 compounds, illicaborins A-C (1-3), were isolated and characterised from the fruits of Illicium arborescens Hayata. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, 1H NMR, 13C NMR, 1H-1H COSY, HMQC, HMBC, and NOESY) including molecular modelling. Compound 1 possesses a new carbon skeleton having a prenylated C6-C3 skeleton with an additional CH2OH group at the C-2 position. The cytotoxic activities of compounds 1-3 were tested and evaluated against Hep-2, Daoy, MCF-7 and WiDr tumour cell lines.
ASJC Scopus subject areas