摘要
Background: Glycine N-methyltransferase (GNMT) is a tumor suppressor of hepatocellular carcinoma (HCC). High proportions of GNMT knockout mice developed HCC. We previously identified a potential novel marker from Gnmt knockout mice, FK506 binding protein 11 (FKBP11). Here, we determined the clinical usefulness of FKBP11. Patients and Methods: FKBP11 expression levels were analyzed in 123 paired tumor and tumor-Adjacent non-tumorous (TA) tissue samples from patients with HCC and in 29 benign liver samples from patients with hemangioma using quantitative real-time polymerase-chain-reaction. Results: FKBP11 was expressed at a higher level in tumor tissues compared to TA tissues (p
原文 | 英語 |
---|---|
頁(從 - 到) | 2763-2770 |
頁數 | 8 |
期刊 | Anticancer Research |
卷 | 33 |
發行號 | 6 |
出版狀態 | 已發佈 - 6月 2013 |
ASJC Scopus subject areas
- 腫瘤科
- 癌症研究