Identification of 7-(4′-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Colorectal Cancer 100%
• Dactolisib 100%
• Cytotoxicity 50%
• Short Hairpin RNA 50%
• Colon Cancer 50%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 50%
• Colorectal Carcinoma 50%
• Cyclin B1 50%
• Microtubule Associated Protein 1 50%
• Mammalian Target of Rapamycin Inhibitor 50%
• Synergism 50%
• Neoplasm 50%
• Caspase 3 50%

Medicine and Dentistry

• Cancer Cell 100%
• Programmed Cell Death 100%
• Colorectal Cancer 100%
• Autophagy 100%
• Mitotic Inhibitor 100%
• Cancer Therapy 50%
• BEZ235 33%
• Therapeutic Agent 16%
• Tumor Cell 16%
• Cell Death 16%
• Short Hairpin RNA 16%
• Cell Cycle M Phase 16%
• Colorectal Carcinoma 16%
• Colon Cancer 16%
• Cyclin B1 16%
• Mammalian Target of Rapamycin Inhibitor 16%
• Light Chain 16%
• Microtubule Associated Protein 1 16%
• Poly ADP Ribose Polymerase 16%
• Cell Line 16%
• Cytotoxicity 16%
• Caspase 3 16%