摘要
The blood perfusion of some tumors is relatively low and poorly responsive to hyperthermia therapy. As a result, the blood flow provides relatively little heat sinking for tumors. We hypothesized that the thermal gradient between tumors and normal tissues could be increased by applying energy only during the pulsation of arteries. Tests of the hypothesis were done by using a finite element model, which simulated a tumor surrounded by normal tissues and this tumor received either continuous or pulsatile heat, together with the pulsatile blood flow. Our results indicated there was a thermal gradient of 8 °C between pulsatile and continuous powers on heat delivery. Established values for tissues and tumors were incorporated into this model and it facilitated us to predict the possible results on hyperthermia therapy.
| 原文 | 英語 |
|---|---|
| 主出版物標題 | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| 發行者 | IEEE |
| 頁面 | 1271 |
| 頁數 | 1 |
| 卷 | 2 |
| ISBN（列印） | 0780356756 |
| 出版狀態 | 已發佈 - 1999 |
| 對外發佈 | 是 |
| 事件 | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA 持續時間: 10月 13 1999 → 10月 16 1999 |
其他
| 其他 | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) |
|---|---|
| 城市 | Atlanta, GA, USA |
| 期間 | 10/13/99 → 10/16/99 |
ASJC Scopus subject areas
- 生物工程