摘要
A modified Windkessel model was used to investigate interactions between peripheral resistance and ejection fraction in determining hypertension. Experimental aortic pressure, Pa(t), and aortic flow, Qa(t), data from mongrel dogs with an average of 23 kg were digitized and then incorporated into a three-element lumped arterial system model. By manipulating peripheral resistance (Rs), systemic capacitance (Cs), and Qa(t), the Pa(t) was studied. Results indicated that elevated Pa(t) caused by increased ejection fraction (EF) can be observed within normal or reduced peripheral impedance. Thus anti-hypertensive drugs using vasodilator could not be effective if cardiac origin of hypertension is involved.
原文 | 英語 |
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主出版物標題 | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
發行者 | IEEE |
頁面 | 247 |
頁數 | 1 |
卷 | 1 |
ISBN(列印) | 0780356756 |
出版狀態 | 已發佈 - 1999 |
對外發佈 | 是 |
事件 | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA 持續時間: 10月 13 1999 → 10月 16 1999 |
其他
其他 | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) |
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城市 | Atlanta, GA, USA |
期間 | 10/13/99 → 10/16/99 |
ASJC Scopus subject areas
- 生物工程