Hypertension of cardiac origin: A model study

J. C. Hsieh, Shih Ann Chen, Cheng Jeng Tai, John K J Li

研究成果: 書貢獻/報告類型會議貢獻

摘要

A modified Windkessel model was used to investigate interactions between peripheral resistance and ejection fraction in determining hypertension. Experimental aortic pressure, Pa(t), and aortic flow, Qa(t), data from mongrel dogs with an average of 23 kg were digitized and then incorporated into a three-element lumped arterial system model. By manipulating peripheral resistance (Rs), systemic capacitance (Cs), and Qa(t), the Pa(t) was studied. Results indicated that elevated Pa(t) caused by increased ejection fraction (EF) can be observed within normal or reduced peripheral impedance. Thus anti-hypertensive drugs using vasodilator could not be effective if cardiac origin of hypertension is involved.
原文英語
主出版物標題Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
發行者IEEE
頁面247
頁數1
1
ISBN(列印)0780356756
出版狀態已發佈 - 1999
對外發佈
事件Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
持續時間: 10月 13 199910月 16 1999

其他

其他Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
城市Atlanta, GA, USA
期間10/13/9910/16/99

ASJC Scopus subject areas

  • 生物工程

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