TY - JOUR
T1 - Hypercalcemia and Lytic Bone Lesions in a Patient with B-Cell Non-Hodgkin's Lymphoma
AU - Jacobs, Renee H.
AU - Larson, Richard A.
AU - Lebeau, Michelle
AU - Kluskens, Larry F.
AU - Vardiman, James W.
AU - Rowley, Janet D.
AU - Golomb, Harvey M.
AU - Bunn, Paul A.
AU - Schechter, Geraldine P.
AU - Whang-Peng, Jacqueline
AU - Jaffe, Elaine
AU - Young, Robert
AU - Blattner, William
AU - Broder, Samuel
AU - Gallo, Robert C.
PY - 1984/1/26
Y1 - 1984/1/26
N2 - To the Editor: Bunn et al. comment that the presence of retrovirus-associated T-cell lymphomas should be strongly suspected on clinical grounds in patients who present with hypercalcemia and metabolic bone abnormalities (Aug. 4 issue).1 In August 1983, we evaluated a 29-year-old white man with painful lytic bone lesions, refractory hypercalcemia (16.0 mg per deciliter), and leukocytosis (53,000 per microliter); 42 percent of the circulating cells resembled poorly differentiated lymphoma cells with marked nuclear clefting and folding. Eleven years earlier the patient had received total-nodal irradiation for Hodgkin's disease (nodular sclerosing), followed two years later by MOPP (mechlorethamine, vincristine, procarbazine,.
AB - To the Editor: Bunn et al. comment that the presence of retrovirus-associated T-cell lymphomas should be strongly suspected on clinical grounds in patients who present with hypercalcemia and metabolic bone abnormalities (Aug. 4 issue).1 In August 1983, we evaluated a 29-year-old white man with painful lytic bone lesions, refractory hypercalcemia (16.0 mg per deciliter), and leukocytosis (53,000 per microliter); 42 percent of the circulating cells resembled poorly differentiated lymphoma cells with marked nuclear clefting and folding. Eleven years earlier the patient had received total-nodal irradiation for Hodgkin's disease (nodular sclerosing), followed two years later by MOPP (mechlorethamine, vincristine, procarbazine,.
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U2 - 10.1056/NEJM198401263100419
DO - 10.1056/NEJM198401263100419
M3 - Letter
C2 - 6318111
AN - SCOPUS:0021369889
SN - 0028-4793
VL - 310
SP - 263
EP - 264
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 4
ER -