High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field

Yu Nan Lin; Peng Chun Chen; Ren Guei Wu; Li Chern Pan; Fan Gang Tseng

High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field

Yu Nan Lin, Peng Chun Chen, Ren Guei Wu, Li Chern Pan, Fan Gang Tseng

研究成果: 書貢獻/報告類型 › 會議貢獻

摘要

In this study, we propose a microfluidic device for differentiating sperm motilities by interacting sperm's flowing upstream property with dual gradient flow field. Non-motile sperms will be flushed out of the second acceleration flow field while the motile sperms will be separated by the first gradient flow field with decreasing flow speed according to their motilities. This gentle sperm sorting process can accumulate millions of motile sperms from billions of sperms in half an hour, and categorized them into 3 different levels, suitable for in vitro fertilization (IVF) and artificial insemination (AI) applications.

原文	英語
主出版物標題	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者	Chemical and Biological Microsystems Society
頁面	645-647
頁數	3
卷	1
ISBN（列印）	9781632666246
出版狀態	已發佈 - 2013
事件	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, 德国持續時間: 10月 27 2013 → 10月 31 2013

其他

其他	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家/地區	德国
城市	Freiburg
期間	10/27/13 → 10/31/13

ASJC Scopus subject areas

生物工程

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引用此

Lin, YN, Chen, PC, Wu, RG, Pan, LC & Tseng, FG 2013, High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field. 於 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. 卷 1, Chemical and Biological Microsystems Society, 頁 645-647, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, Freiburg, 德国, 10/27/13.

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abstract = "In this study, we propose a microfluidic device for differentiating sperm motilities by interacting sperm's flowing upstream property with dual gradient flow field. Non-motile sperms will be flushed out of the second acceleration flow field while the motile sperms will be separated by the first gradient flow field with decreasing flow speed according to their motilities. This gentle sperm sorting process can accumulate millions of motile sperms from billions of sperms in half an hour, and categorized them into 3 different levels, suitable for in vitro fertilization (IVF) and artificial insemination (AI) applications.",

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AB - In this study, we propose a microfluidic device for differentiating sperm motilities by interacting sperm's flowing upstream property with dual gradient flow field. Non-motile sperms will be flushed out of the second acceleration flow field while the motile sperms will be separated by the first gradient flow field with decreasing flow speed according to their motilities. This gentle sperm sorting process can accumulate millions of motile sperms from billions of sperms in half an hour, and categorized them into 3 different levels, suitable for in vitro fertilization (IVF) and artificial insemination (AI) applications.

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BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

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High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field

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