Hepatitis B virus infection and the risk of male infertility: A population-based analysis

Fu-Hsiung Su, Shih Ni Chang, Fung Chang Sung, Chien-Tien Su, Ying-Hua Shieh, Cheng Chieh Lin, Chih-Ching Yeh

研究成果: 雜誌貢獻文章同行評審

32 引文 斯高帕斯(Scopus)


Objective: To evaluate the risk of male infertility among patients with hepatitis B virus (HBV) infection. Design: A nationwide, population-based cohort study. Setting: Not applicable. Patient(s): Men infected with HBV (n = 5,138) and men without HBV infection (n = 25,690). Intervention(s): None. Main Outcome Measure(s): Male infertility, as defined by the International Classification of Diseases, Ninth Revision, Clinical Modification. Result(s): The incidence of infertility was 1.59 times higher in patients with HBV infection than in those without HBV infection (2.21 vs. 1.39 per 1,000 person-years). The risk of developing infertility remained significant among patients with HBV infection (hazard ratio 1.52, 95% confidence interval 1.20-1.92) after adjusting for covariates in a multivariate Cox proportional hazards model. Conclusion(s): The data show an increased incidence and risk of infertility among men with HBV infection compared with men without HBV.
頁(從 - 到)1677-1684
期刊Fertility and Sterility
出版狀態已發佈 - 12月 1 2014

ASJC Scopus subject areas

  • 生殖醫學
  • 婦產科


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