Gross hematuria and IgA nephropathy flare-up following the first dose of Moderna vaccine A case report

Po Hung Tseng, Shu Han Chuang, Yueh Pan, Hung Jen Shih, Chin Pao Chang, Sheng Hsien Huang

研究成果: 雜誌貢獻文章同行評審

摘要

Background: Since the mass vaccination for COVID-19, several case reports indicated the risk of autoimmune disease flareups after the vaccination. Among them, COVID-19 vaccine-induced glomerular diseases have drawn attention worldwide. The cases demonstrating the association between the mRNA vaccine and IgA nephropathy (IgAN) exacerbation had been noticed. Mostly mentioned, the flare-ups usually occurred after the second dose. Methods: We present a Taiwanese female with IgAN who developed gross hematuria within only six hours after the first dose of the Moderna vaccine. Results: Six hours after the first dose of Moderna vaccine on 8 June 2021, the patient developed gross hematuria and significantly decreased urine output. All symptoms resolved spontaneously on the fifth day after the vaccination without any intervention. On the fourth day after the vaccination, the patient were able to back to her original condition. Conclusion: This was an intriguing case of IgAN flare-up following the first dose of mRNA-based COVID-19 vaccination.
原文英語
文章編號e32524
期刊Medicine (United States)
101
發行號52
DOIs
出版狀態已發佈 - 12月 2022

ASJC Scopus subject areas

  • 一般醫學

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