TY - JOUR
T1 - FORMULATION AND ACTIVITY TEST OF SUNFLOWER OIL (HELIANTHUS ANNUUS L.) LIQUID SOAP AS ANTI ACNE
AU - Iskandar, Benni
AU - Putri, Rani Septiana
AU - Novita, Gressy
AU - Surboyo, Meircurius Dwi Condro
AU - Leny,
AU - Lee, Ching Kuo
N1 - Funding Information:
This research was conducted at the Pharmaceutical Laboratory, Laboratory of Natural Material Pharmacy, Research and Biopharmaceutical Laboratory, and Sekolah Tinggi Ilmu Farmasi Riau.
Publisher Copyright:
© 2022 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
PY - 2022/6
Y1 - 2022/6
N2 - Objective: This study aims to obtain a liquid soap containing sunflower oil which has a good physical characteristics and stability, also has potential as an antibacterial towards acne bacteria. Methods: Sunflower oil is formulated into liquid facial wash with various concentrations 10% (F1); 15% (F2); and 20% (F3). Evaluation of preparations includes organoleptic test, pH value, specific gravity, viscosity, foaming ability, foam stability, freeze and thaw stability, and antibacterial activity against Propionibacterium acnes which causes acne by using the disc diffusion method. Data obtained was analyzed using Kruskal Wallis statistical test, One Way ANOVA, and descriptive test. Results: Based on the results of the evaluation of the preparations, it was found that the organoleptic examination of F1, F2, and F3 liquid soap preparations had a thick liquid form, milky white in color, with the smell of rose. Liquid facial wash preparations of F1, F2, and F3 meet the evaluation requirements of pH, specific gravity, viscosity, ability to form foam, stable during storage in various degrees. Based on the analysis of the One Way ANOVA statistical test, there was a significant difference (p<0.05) in the diameter of the inhibition zone between each group of formulas. Conclusion: It was concluded that the liquid facial wash preparations of sunflower oil F1, F2, and F3 were physically stable during storage, and based on the antibacterial activity test it was known that F3 had the greatest bacterial inhibition with a strong inhibition category (32.19±0.36 mm).
AB - Objective: This study aims to obtain a liquid soap containing sunflower oil which has a good physical characteristics and stability, also has potential as an antibacterial towards acne bacteria. Methods: Sunflower oil is formulated into liquid facial wash with various concentrations 10% (F1); 15% (F2); and 20% (F3). Evaluation of preparations includes organoleptic test, pH value, specific gravity, viscosity, foaming ability, foam stability, freeze and thaw stability, and antibacterial activity against Propionibacterium acnes which causes acne by using the disc diffusion method. Data obtained was analyzed using Kruskal Wallis statistical test, One Way ANOVA, and descriptive test. Results: Based on the results of the evaluation of the preparations, it was found that the organoleptic examination of F1, F2, and F3 liquid soap preparations had a thick liquid form, milky white in color, with the smell of rose. Liquid facial wash preparations of F1, F2, and F3 meet the evaluation requirements of pH, specific gravity, viscosity, ability to form foam, stable during storage in various degrees. Based on the analysis of the One Way ANOVA statistical test, there was a significant difference (p<0.05) in the diameter of the inhibition zone between each group of formulas. Conclusion: It was concluded that the liquid facial wash preparations of sunflower oil F1, F2, and F3 were physically stable during storage, and based on the antibacterial activity test it was known that F3 had the greatest bacterial inhibition with a strong inhibition category (32.19±0.36 mm).
KW - Antibacterial
KW - Liquid facial wash
KW - Propionibacterium acne
KW - Sunflower oil
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U2 - 10.22159/ijap.2022.v14s3.11
DO - 10.22159/ijap.2022.v14s3.11
M3 - Article
AN - SCOPUS:85133953234
SN - 0975-7058
VL - 14
SP - 55
EP - 59
JO - International Journal of Applied Pharmaceutics
JF - International Journal of Applied Pharmaceutics
IS - Special Issue 3
ER -