@article{67aaa972663348f8a709bb9c72f25e41,
title = "Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis",
abstract = "Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.",
keywords = "defective spermiogenesis, Intracytoplasmic spermatid injection, obstructive azoospermia",
author = "Chen, \{S. U.\} and Ho, \{H. N.\} and Chen, \{H. F.\} and Tsai, \{T. C.\} and Lee, \{T. Y.\} and Yang, \{Y. S.\}",
note = "Funding Information: Received September 12, 1995; revised and accepted February 5,1996. * Supported in part by grants from the National Science Council (NSC-82-412-B002-343), Taipei, Taiwan. t Department of Obstetrics and Gynecology. :\textbackslash{}: Reprint requests: Hong-Nerng Ho, M.D., Department of Obstetrics and Gynecology, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, Taiwan (FAX: 886-2-3418557). § Department of Urology.",
year = "1996",
month = jan,
day = "1",
doi = "10.1016/s0015-0282(16)58406-4",
language = "English",
volume = "66",
pages = "157--160",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "1",
}