摘要
The aim of this study was to incorporate nanoscale Fe3O4 particles into a poly-L-lactide (PLLA) matrix to fabricate a magnetic and biodegradable composite. The physical and osteogenic functions of this material were tested. Injection molding was used to fabricate four nano-Fe3O4/PLLA composites with Fe3O4 mix ratios of 0%, 20%, 30%, and 40% (w/w). X-ray diffraction and hysteresis loop tests were performed to evaluate the physical properties of the nano-Fe3O4/PLLA composites. Tensile strength tests showed that the progressive addition of nano-Fe3O4 particles to the PLLA matrix results in higher elastic modulus and lower tensile strength. Images from scanning electron microscopy demonstrated that osteoblasts cultured on the 20% nano-Fe3O4/PLLA surface exhibited abundant filaments, which are a morphologic characteristic of osteoblastic differentiation. These results suggest that the 20% nano-Fe3O4/PLLA composite used in this study has the potential for future tissue engineering applications.
原文 | 英語 |
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頁(從 - 到) | 2881-2888 |
頁數 | 8 |
期刊 | Polymer Composites |
卷 | 38 |
發行號 | 12 |
DOIs | |
出版狀態 | 已發佈 - 12月 2017 |
ASJC Scopus subject areas
- 一般化學
- 陶瓷和複合材料
- 材料化學
- 聚合物和塑料