TY - JOUR
T1 - Extreme temperature increases the risk of COPD morbimortality
T2 - A systematic review and meta-analysis
AU - Tran, Huan Minh
AU - Tsai, Feng Jen
AU - Lee, Kang Yun
AU - Wang, Yuan Hung
AU - Yang, Feng Ming
AU - Ho, Shu Chuan
AU - Bui, Hanh Thi My
AU - Hoang, Linh Nhat Nguyen
AU - Bui, Linh Thi My
AU - Ho, Kin Fai
AU - Chung, Kian Fan
AU - Chuang, Kai Jen
AU - Chuang, Hsiao Chi
N1 - Publisher Copyright:
© 2024 Elsevier B.V.
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Introduction: This systematic review examines how extreme temperatures impact chronic obstructive pulmonary disease (COPD) morbidity and mortality, focusing on identifying vulnerable subpopulations. Methods: We conducted a systematic literature search from January 1, 2000, to November 6, 2024, across databases like PubMed, MEDLINE and EMBASE, Web of Science, and Scopus, focusing on observational studies that quantitatively defined extreme temperatures and their impacts on COPD morbidity and mortality. Out of 3140 records, 25 studies met the inclusion criteria. We extracted data on study characteristics, effect estimates, and confounders, employing methods to assess the risk of bias and synthesize results. Results: We observed that extreme heat increased the relative risk (RR) for COPD morbimortality by 1.16-fold (95 % CI: 1.08–1.26; p < 0.05), and extreme cold increased the RR by 1.32-fold (95 % CI: 1.20–1.46;). Extreme heat was associated with a 1.19-fold (95 % CI: 1.09–1.30; p < 0.05) increase in COPD mortality. In contrast, extreme cold was associated with both COPD morbidity and mortality, with morbidity increasing by 1.47-fold (95 % CI: 1.26–1.71; p < 0.05) and mortality by 1.23-fold (95 % CI: 1.10–1.38; p < 0.05). Extreme heat poses a higher risk for female COPD patients compared to males. Moreover, extreme heat and cold were associated with morbimortality risk among older adults. Asian populations were sensitive to both temperature extremes, whereas Europeans were predominantly susceptible to extreme cold. Conclusion: This variability in response to extreme temperatures affects COPD morbidity and mortality, emphasizing the need for tailored medical and emergency responses to effectively mitigate health risks during extreme weather events.
AB - Introduction: This systematic review examines how extreme temperatures impact chronic obstructive pulmonary disease (COPD) morbidity and mortality, focusing on identifying vulnerable subpopulations. Methods: We conducted a systematic literature search from January 1, 2000, to November 6, 2024, across databases like PubMed, MEDLINE and EMBASE, Web of Science, and Scopus, focusing on observational studies that quantitatively defined extreme temperatures and their impacts on COPD morbidity and mortality. Out of 3140 records, 25 studies met the inclusion criteria. We extracted data on study characteristics, effect estimates, and confounders, employing methods to assess the risk of bias and synthesize results. Results: We observed that extreme heat increased the relative risk (RR) for COPD morbimortality by 1.16-fold (95 % CI: 1.08–1.26; p < 0.05), and extreme cold increased the RR by 1.32-fold (95 % CI: 1.20–1.46;). Extreme heat was associated with a 1.19-fold (95 % CI: 1.09–1.30; p < 0.05) increase in COPD mortality. In contrast, extreme cold was associated with both COPD morbidity and mortality, with morbidity increasing by 1.47-fold (95 % CI: 1.26–1.71; p < 0.05) and mortality by 1.23-fold (95 % CI: 1.10–1.38; p < 0.05). Extreme heat poses a higher risk for female COPD patients compared to males. Moreover, extreme heat and cold were associated with morbimortality risk among older adults. Asian populations were sensitive to both temperature extremes, whereas Europeans were predominantly susceptible to extreme cold. Conclusion: This variability in response to extreme temperatures affects COPD morbidity and mortality, emphasizing the need for tailored medical and emergency responses to effectively mitigate health risks during extreme weather events.
KW - Chest
KW - Climate change
KW - COPD
KW - Extreme weather
KW - Respiratory
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U2 - 10.1016/j.scitotenv.2024.178087
DO - 10.1016/j.scitotenv.2024.178087
M3 - Review article
AN - SCOPUS:85212139626
SN - 0048-9697
VL - 958
JO - Science of the Total Environment
JF - Science of the Total Environment
M1 - 178087
ER -