TY - JOUR
T1 - Exploring associations of clinical and social parameters with violent behaviors among psychiatric patients
AU - Dai, Hong Jie
AU - Su, Emily Chia Yu
AU - Uddin, Mohy
AU - Jonnagaddala, Jitendra
AU - Wu, Chi Shin
AU - Syed-Abdul, Shabbir
N1 - Funding Information:
The study was supported by the following grants: Ministry of Science and Technology (MOST) 103-2221-E-038-014 , MOST 103-2221-E-038-016 , MOST 104-2221-E-038-013 , MOST 104-3011-E-038-001 , and MOST 105-2221-E-143-003 , Health and Welfare Surcharge of Tobacco Products grant MOHW 104-TDU-B-212-124-001 , and Ministry of Education grant TMUTOP103006-6 . Two grants made the organization of the CEGS N-GRID 2016 shared task possible: NIH P50 MH106933 (to PI: Isaac Kohane) and NIH 4R13LM011411 (to PI: Ozlem Uzuner).
PY - 2017/11
Y1 - 2017/11
N2 - Evidence has revealed interesting associations of clinical and social parameters with violent behaviors of patients with psychiatric disorders. Men are more violent preceding and during hospitalization, whereas women are more violent than men throughout the 3. days following a hospital admission. It has also been proven that mental disorders may be a consistent risk factor for the occurrence of violence. In order to better understand violent behaviors of patients with psychiatric disorders, it is important to investigate both the clinical symptoms and psychosocial factors that accompany violence in these patients. In this study, we utilized a dataset released by the Partners Healthcare and Neuropsychiatric Genome-scale and RDoC Individualized Domains project of Harvard Medical School to develop a unique text mining pipeline that processes unstructured clinical data in order to recognize clinical and social parameters such as. age, gender, history of alcohol use, and violent behaviors, and explored the associations between these parameters and violent behaviors of patients with psychiatric disorders. The aim of our work was to demonstrate the feasibility of mining factors that are strongly associated with violent behaviors among psychiatric patients from unstructured psychiatric evaluation records using clinical text mining. Experiment results showed that stimulants, followed by a family history of violent behavior, suicidal behaviors, and financial stress were strongly associated with violent behaviors. Key aspects explicated in this paper include employing our text mining pipeline to extract clinical and social factors linked with violent behaviors, generating association rules to uncover possible associations between these factors and violent behaviors, and lastly the ranking of top rules associated with violent behaviors using statistical analysis and interpretation.
AB - Evidence has revealed interesting associations of clinical and social parameters with violent behaviors of patients with psychiatric disorders. Men are more violent preceding and during hospitalization, whereas women are more violent than men throughout the 3. days following a hospital admission. It has also been proven that mental disorders may be a consistent risk factor for the occurrence of violence. In order to better understand violent behaviors of patients with psychiatric disorders, it is important to investigate both the clinical symptoms and psychosocial factors that accompany violence in these patients. In this study, we utilized a dataset released by the Partners Healthcare and Neuropsychiatric Genome-scale and RDoC Individualized Domains project of Harvard Medical School to develop a unique text mining pipeline that processes unstructured clinical data in order to recognize clinical and social parameters such as. age, gender, history of alcohol use, and violent behaviors, and explored the associations between these parameters and violent behaviors of patients with psychiatric disorders. The aim of our work was to demonstrate the feasibility of mining factors that are strongly associated with violent behaviors among psychiatric patients from unstructured psychiatric evaluation records using clinical text mining. Experiment results showed that stimulants, followed by a family history of violent behavior, suicidal behaviors, and financial stress were strongly associated with violent behaviors. Key aspects explicated in this paper include employing our text mining pipeline to extract clinical and social factors linked with violent behaviors, generating association rules to uncover possible associations between these factors and violent behaviors, and lastly the ranking of top rules associated with violent behaviors using statistical analysis and interpretation.
KW - Association rule mining
KW - Odds ratio
KW - Psychiatric evaluation record
KW - Text mining
KW - Violent behavior
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U2 - 10.1016/j.jbi.2017.08.009
DO - 10.1016/j.jbi.2017.08.009
M3 - Article
AN - SCOPUS:85028326092
SN - 1532-0464
VL - 75
SP - S149-S159
JO - Journal of Biomedical Informatics
JF - Journal of Biomedical Informatics
ER -