TY - JOUR
T1 - Evaluation of Nitroglycerin Premedication on the Arterial Luminal Diameter and Branches of Coronary Arteries on 64-Multidetector Computed Tomography Angiography
AU - Lee, Chi-Ming
AU - Wang, Hung Jung
AU - Kung, Ching Huei
AU - Lin, Yi Hsiang
AU - Leung, Ting-Kai
AU - Huang, Chun-Yao
AU - Shih, Chun-Ming
AU - Hsiao, Wen Tien
AU - Chen, Ya Yen
PY - 2011/4
Y1 - 2011/4
N2 - Background: The 64-multidetector computed tomography (64-MDCT) has developed into a mature clinical tool to detect coronary artery disease. This 64-MDCT system permits cross-sectional and longitudinal imaging of the coronary arteries with a high spatial and temporal resolution. However, small vessels, side branches and the distal portions of the main coronary arteries are not always optimally visualized. Purpose: The aim of this study was to evaluate the effect of nitroglycerin (NTG) on lumen diameters and the number of visualized side branches of the coronary arteries on 64-MDCT. We also assessed whether NTG would affect the quality of the images of the coronary arteries obtained by 64-MDCT. Methods: Sixty-seven patients were randomized and divided into two groups: Group C (31 patients, no sublingual NTG) and Group N (36 patients, sublingual NTG given before the scan). We measured the lumen diameter of the coronary artery and visibility of the side branches by using the 64-MDCT system and also evaluated the image quality by using the scores. Results: The cardiac 64-MDCT images of these patients showed that the average diameters of the proximal segments in the right coronary artery, left main artery, left anterior descending coronary artery, and left circumflex coronary artery were 4.1 ± 0.7. mm, 3.9 ± 0.6. mm, 3.6 ± 0.7. mm, and 3.4 ± 0.6. mm, respectively, in Group N and 3.0 ± 0.5. mm, 3.1 ± 0.6. mm, 2.8 ± 0.5. mm, and 2.7 ± 0.5. mm, respectively in Group C. In addition, the scores for visibility and image quality for the side branches in Group N were significant higher than for those in Group C. Conclusion: Our study indicates that CT coronary angiography using 64-MDCT with NTG administration produces images of diagnostically acceptable quality in all coronary segments. Thus, NTG might be recommended for routine 64-MDCT coronary angiography examinations.
AB - Background: The 64-multidetector computed tomography (64-MDCT) has developed into a mature clinical tool to detect coronary artery disease. This 64-MDCT system permits cross-sectional and longitudinal imaging of the coronary arteries with a high spatial and temporal resolution. However, small vessels, side branches and the distal portions of the main coronary arteries are not always optimally visualized. Purpose: The aim of this study was to evaluate the effect of nitroglycerin (NTG) on lumen diameters and the number of visualized side branches of the coronary arteries on 64-MDCT. We also assessed whether NTG would affect the quality of the images of the coronary arteries obtained by 64-MDCT. Methods: Sixty-seven patients were randomized and divided into two groups: Group C (31 patients, no sublingual NTG) and Group N (36 patients, sublingual NTG given before the scan). We measured the lumen diameter of the coronary artery and visibility of the side branches by using the 64-MDCT system and also evaluated the image quality by using the scores. Results: The cardiac 64-MDCT images of these patients showed that the average diameters of the proximal segments in the right coronary artery, left main artery, left anterior descending coronary artery, and left circumflex coronary artery were 4.1 ± 0.7. mm, 3.9 ± 0.6. mm, 3.6 ± 0.7. mm, and 3.4 ± 0.6. mm, respectively, in Group N and 3.0 ± 0.5. mm, 3.1 ± 0.6. mm, 2.8 ± 0.5. mm, and 2.7 ± 0.5. mm, respectively in Group C. In addition, the scores for visibility and image quality for the side branches in Group N were significant higher than for those in Group C. Conclusion: Our study indicates that CT coronary angiography using 64-MDCT with NTG administration produces images of diagnostically acceptable quality in all coronary segments. Thus, NTG might be recommended for routine 64-MDCT coronary angiography examinations.
KW - 64-MDCT
KW - Coronary angiography
KW - Nitroglycerin
UR - http://www.scopus.com/inward/record.url?scp=79954756931&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79954756931&partnerID=8YFLogxK
U2 - 10.1016/j.jecm.2010.12.011
DO - 10.1016/j.jecm.2010.12.011
M3 - Article
AN - SCOPUS:79954756931
SN - 1878-3317
VL - 3
SP - 85
EP - 88
JO - Journal of Experimental and Clinical Medicine(Taiwan)
JF - Journal of Experimental and Clinical Medicine(Taiwan)
IS - 2
ER -