Evaluating the feasibility of applying cobalt-hydroxyapatite ingots as radiotherapy markers

Wei Chun Lin, Cheng Ming Tang, Cheng Chang Lu, Chun Chao Chuang

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)


The substitution of cobalt for calcium in hydroxyapatite produces CoHA with a higher effective atomic number. This study evaluates various medical imaging characteristics of round CoHA ingots in a porcine phantom to demonstrate the feasibility of using CoHA ingots as radiotherapy markers. CoHA was compressed into round ingots and then implanted into a porcine liver phantom and a gelatin porcine vertebra phantom along with three commercially available radiotherapy markers. The phantom was respectively scanned and photographed using a routine x-ray imager, magnetic resonance imager, computed tomography (CT) imager, and ultrasound imager followed by image analysis in ImageJ software. CoHA ingots could be clearly identified with general imaging instruments (x-ray, CT, and ultrasound) and the image size did not change. There were some metal artifacts in the magnetic resonance images. Biodegradable CoHA ingots can be self-absorbed by the body over time to avoid interference with follow-up disease screening and can be used with most medical imaging instruments quickly to help identify the location and extent of soft-tissue tumors.
期刊Materials Today Communications
出版狀態已發佈 - 9月 2020

ASJC Scopus subject areas

  • 一般材料科學
  • 材料力學
  • 材料化學


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