@article{0d0ce60891bc41e1adc01eaace9835ec,
title = "Endoscopic Enucleation of Prostate Could Increase Testosterone Levels in Hypotestosteronemic Patients with Bladder Outlet Obstruction",
abstract = "Background: We evaluated the impact of endoscopic enucleation of the prostate on testosterone levels in hypotestosteronemic patients with bladder outlet obstruction. Methods: We enrolled 294 men with lower urinary tract symptoms (LUTS) who received surgery between January 2019 and December 2020 in simple tertiary centre. The inclusion criteria were as follows: being a male patient aged 45–95 years and having recurrent urinary tract infection, having previously failed medical treatment for LUTS or urine retention, and undergoing bipolar or thulium laser enucleation of the prostate. The preoperative and postoperative data were retrospectively reviewed. Results: This study included 112 men with a mean age of 69.4 years. The mean preoperative and postoperative testosterone levels were 4.8 and 4.98, respectively. Of the patients, 88 (78.6%) received ThuLEP and 24 received BipolEP. We divided the patients into two groups according to preoperative serum testosterone levels: normal-testosterone (≥3 ng/mL) and low-testosterone (<3 ng/mL) groups. A significant change in testosterone levels (p = 0.025) was observed in the low-testosterone group. In contrast, no significant difference in testosterone levels was noted in the normal-testosterone group (p = 0.698). Conclusions: Endoscopic enucleation surgery of the prostate could improve postoperative testosterone levels in hypotestosteronemic patients with bladder outlet obstruction.",
keywords = "benign prostatic hyperplasia, BipolEP, circadian rhythm, secondary hypogonadism, testosterone, ThuLEP",
author = "Li, {Yun Ren} and Tsao, {Shu Han} and Chen, {Chien Lun} and Hou, {Chen Pang} and Tsui, {Ke Hung} and Juang, {Horng Heng} and Lin, {Yu Hsiang}",
note = "Funding Information: The authors thank the statistical assistance and wish to acknowledge the support of the Maintenance Project of the Centre for Big Data Analytics and Statistics (Grant CLRPG3D0049) at Chang Gung Memorial Hospital for study design and monitor, data analysis and interpretation. Funding Information: This study was funded by the Chang Gung Memorial Hospital, Grant number: CMRPG3K2371. Publisher Copyright: {\textcopyright} 2022 by the authors.",
year = "2022",
month = nov,
doi = "10.3390/jcm11226808",
language = "English",
volume = "11",
journal = "Journal of Clinical Medicine",
issn = "2077-0383",
number = "22",
}