Endoplasmic reticulum stress-triggered autophagy and lysosomal dysfunction contribute to the cytotoxicity of amine-modified silver nanoparticles in NIH 3T3 cells

Engineering & Materials Science

• Cytotoxicity 88%
• Silver nanoparticles 86%
• Amines 71%
• Biological systems 69%
• Cells 58%
• Oxidative stress 51%
• Cell death 44%
• Nanostructured materials 37%
• Toxicity 35%
• Swelling 33%
• Nanoparticles 29%
• Chemical activation 26%
• Substrates 21%

Chemical Compounds

• P62 100%
• Cell Death 64%
• Oxidative Stress 59%
• Silver Nanoparticle 53%
• Marker 52%
• Protective 49%
• Toxic 45%
• Antimicrobial Agent 42%
• Amine 38%
• Nanomaterial 37%
• Application 18%

Medicine & Life Sciences

• NIH 3T3 Cells 77%
• Endoplasmic Reticulum Stress 66%
• Silver 64%
• Amines 63%
• Autophagy 57%
• Nanoparticles 53%
• Autophagosomes 29%
• Lysosomes 24%
• Nanostructures 14%
• Endocytosis 12%
• Toxicology 11%
• Cell Death 9%
• Poisons 8%
• Oxidative Stress 8%