Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Po Liang Lin; Hsu Wei Fang; Tiffany Tseng; Wun Hsing Lee

doi:10.1016/j.matlet.2006.10.064

Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Po Liang Lin, Hsu Wei Fang, Tiffany Tseng, Wun Hsing Lee

研究成果: 雜誌貢獻 › 文章 › 同行評審

74 引文斯高帕斯（Scopus）

摘要

Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

原文	英語
頁（從 - 到）	3009-3013
頁數	5
期刊	Materials Letters
卷	61
發行號	14-15
DOIs	https://doi.org/10.1016/j.matlet.2006.10.064
出版狀態	已發佈 - 6月 1 2007
對外發佈	是

ASJC Scopus subject areas

一般材料科學
凝聚態物理學
材料力學
機械工業

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10.1016/j.matlet.2006.10.064

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title = "Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials",

abstract = "Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.",

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AU - Lin, Po Liang

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AU - Tseng, Tiffany

AU - Lee, Wun Hsing

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Y1 - 2007/6/1

N2 - Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

AB - Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

KW - Cell proliferation

KW - Composite

KW - Hydroxyapatite

KW - Mechanical strength

KW - Polylactic acid

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Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

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