TY - JOUR
T1 - Effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer
AU - Chao, Jane Chen Jui
AU - Hung, Huei Chen
AU - Chen, Sheng-Hsuan
AU - Fang, Chia Lang
PY - 2004/2/15
Y1 - 2004/2/15
N2 - Aim: To investigate the effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer. Methods: Sprague-Dawley rats were randomly divided into four groups: sham operation without ginkgo, sham operation with ginkgo, duodenal ulcer without ginkgo, and duodenal ulcer with ginkgo. Rats with duodenal ulcer were induced by 500 mL/L acetic acid. Rats with ginkgo were intravenously injected with Ginkgo biloba extract from the tail at a dose of 0.5 mg/(kg.d) for 7 and 14 days. Results: Pathological result showed that duodenal ulcer rats with ginkgo improved mucosal healing and inflammation compared with those without ginkgo after 7 d treatment. After 14 d treatment, duodenal ulcer rats with ginkgo significantly increased weight gain (34.0±4.5 g versus 24.5±9.5 g, P2 concentration significantly increased by 129% (P
AB - Aim: To investigate the effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer. Methods: Sprague-Dawley rats were randomly divided into four groups: sham operation without ginkgo, sham operation with ginkgo, duodenal ulcer without ginkgo, and duodenal ulcer with ginkgo. Rats with duodenal ulcer were induced by 500 mL/L acetic acid. Rats with ginkgo were intravenously injected with Ginkgo biloba extract from the tail at a dose of 0.5 mg/(kg.d) for 7 and 14 days. Results: Pathological result showed that duodenal ulcer rats with ginkgo improved mucosal healing and inflammation compared with those without ginkgo after 7 d treatment. After 14 d treatment, duodenal ulcer rats with ginkgo significantly increased weight gain (34.0±4.5 g versus 24.5±9.5 g, P2 concentration significantly increased by 129% (P
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M3 - Article
C2 - 14966917
AN - SCOPUS:1542345020
SN - 1007-9327
VL - 10
SP - 560
EP - 566
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
IS - 4
ER -