@article{2e22f20cdf014ee8a91178ee33d9f2aa,
title = "Effects of concurrent chemoradiotherapy on the metastasis and the mesenchymal transition of bladder urothelial carcinoma cells",
abstract = "Background/Aim: Cancer stem cells (CSCs) have been suggested playing a crucial role in the tumorigenesis and tumor progression. Clinically, concurrent chemoradiotherapy (CCRT) after transurethral resection of the bladder is the widely accepted treatment option for high-grade bladder urothelial carcinoma (UC); however, a proportion of bladder UC patients still suffer from recurrence and metastasis. In the present study, we investigated the stemness properties of bladder UC cells with respect to various disease stages. The metastatic capability and epithelial–mesenchymal transition (EMT) of the parental cells and the CSC cells of bladder UC",
keywords = "Bladder urothelial carcinoma, Cancer stem cell, Chemoradioresistance, Concurrent chemoradiotherapy, Epithelial–mesenchymal transition",
author = "Yueh Pan and Hong, {Ying Chui} and Hsiao, {Chi Hao} and Shih, {Hung Jen} and Huang, {Sheng Hsien} and Wu, {Sheng Chuan} and Chang, {Chin Pao} and Chiu, {Shao Chi} and Cho, {Der Yang} and Shih, {Ping Hsiao}",
note = "Funding Information: The present study was supported by grants from the Research Fund of the Department of Medical Research, China Medical University Hospital (grant nos. DMR-107-153 and DMR-CELL-1809) and Taipei Municipal WanFang Hospital (grant no.109-wf-eva-28). We also thanked Ya-Hsu Chiu for technological support. Publisher Copyright: {\textcopyright} 2021 International Institute of Anticancer Research. All rights reserved.",
year = "2021",
month = oct,
doi = "10.21873/anticanres.15309",
language = "English",
volume = "41",
pages = "4957--4968",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "10",
}
