Effect of Obesity and Vitamin D Levels on Outcome Prediction in Critical Patients

I. Ting Wang, Hsiu Wu Yang, Kuo Song Chang, Yu Jang Su, Chung Wei Chen, Kuo Ching Yuan, An Yi Wang, Yin Chin Wang, Yin Yi Han, Li Kuo Kuo, Yu Chang Yeh

研究成果: 雜誌貢獻文章同行評審

摘要

Background: Vitamin D is an important nutrient for maintaining cardiovascular, endocrine, immune, and nervous system health. Body mass index (BMI) is one of the factors influencing vitamin D levels. We aimed to study the factors that play a role in the outcomes and prognoses of critically ill patients. Method: This study was conducted at four teaching hospitals in Northern Taiwan between August 2018 and July 2020. A total of 1421 critically ill patients admitted to the intensive care units (ICUs) were eligible for assessment. Patients were classified into two groups based on serum 25(OH)D levels: sufficiency (3 20 ng/ml) and insufficiency (< 20 ng/ml); and into four groups according to BMI: underweight (BMI < 18.5), normal weight (BMI 18.5–24.9), overweight (BMI 25–29.9), and obesity (BMI 3 30). Statistical analyses were performed, and a p-value < 0.05 indicated a significant difference. Results: More than half (57.9%) of the critically ill ICU patients had vitamin D deficiency (VDD); and VDD lengthened ICU stay by 2.5 days in vitamin D-deficit patients as compared to that in vitamin D-sufficient patients. Patients with obesity had a 4.2-day longer ICU stay (16.7 days) than that of the BMI < 30 group (12.5 days), which was significant (p = 0.009). They also had the lowest vitamin D levels (17.3 ng/mL) and the highest 90-day mortality rate (17.3%) compared to the other BMI groups. Conclusion: In caring for critical patients, physicians need to pay more attention to vitamin D levels and BMI factors, which may impact their outcome prediction.
原文英語
頁(從 - 到)237-242
頁數6
期刊International Journal of Gerontology
17
發行號4
DOIs
出版狀態已發佈 - 2023

ASJC Scopus subject areas

  • 老年病學和老年學

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