Effect of liver cirrhosis on long-term outcomes after acute respiratory failure: A population-based study

Chih Cheng Lai, Chung Han Ho, Kuo Chen Cheng, Chien Ming Chao, Chin Ming Chen, Willy Chou

研究成果: 雜誌貢獻文章同行評審

8 引文 斯高帕斯(Scopus)

摘要

AIM To assessed the effect of liver cirrhosis (LC) on the poorly understood long-term mortality risk after firstever mechanical ventilation (1-MV) for acute respiratory failure. METHODS All patients in Taiwan given a 1-MV between 1997 and 2013 were identified in Taiwan's Longitudinal Health Insurance Database 2000. Each patient with LC was individually matched, using a propensity-score method, to two patients without LC. The primary outcome was death after a 1-MV. RESULTS A total of 16653 patients were enrolled: 5551 LC-positive (LC[Pos]) patients, including 1732 with cryptogenic LCs and 11102 LC-negative (LC[Neg]) controls. LC[Pos] patients had more organ failures and were more likely to be admitted to medical department than were LC[Neg] controls. LC[Pos] patients had a significantly lower survival rate (AHR = 1.38, 95%CI: 1.32-1.44). Moreover, the mortality risk was significantly higher for patients with non-cryptogenic LC than for patients with cryptogenic LC (AHR = 1.43, 95%CI: 1.32-1.54) and patients without LC (AHR = 1.56, 95%CI: 1.32-1.54). However, there was no significant difference between patients with cryptogenic and without LC (HR = 1.05, 95%CI: 0.98-1.12). CONCLUSION LC, especially non-cryptogenic LC, significantly increases the risk of death after a 1-MV. © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
原文英語
頁(從 - 到)2201-2208
頁數8
期刊World Journal of Gastroenterology
23
發行號12
DOIs
出版狀態已發佈 - 3月 28 2017
對外發佈

ASJC Scopus subject areas

  • 消化內科

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