摘要
原文 | 英語 |
---|---|
頁(從 - 到) | 315-319 |
頁數 | 5 |
期刊 | International Journal of Surgery |
卷 | 12 |
發行號 | 4 |
DOIs | |
出版狀態 | 已發佈 - 2014 |
對外發佈 | 是 |
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於: International Journal of Surgery, 卷 12, 編號 4, 2014, p. 315-319.
研究成果: 雜誌貢獻 › 文章 › 同行評審
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TY - JOUR
T1 - Early predictors for tissue healing deficit and leakage in geriatric critically ill patients receiving emergent abdominal surgery: A case control study
AU - Wu, Shih-Chi
AU - Fu, Chih-Yuan
AU - Hsieh, Chi-Hsun
AU - Wang, Yu-Chun
AU - Lo, Hung-Chieh
AU - Cheng, Han-Tsung
AU - Tzeng, Chia-Wei
N1 - 被引用次數:1 Export Date: 24 March 2016 通訊地址: Wu, S.-C.; Trauma and Emergency Center, China Medical University Hospital, No. 2 Yuh-Der Road, Taichung 404, Taiwan; 電子郵件: rw114@mail.cmuh.org.tw 化學物質/CAS: adrenalin, 51-43-4, 55-31-2, 6912-68-1; dopamine, 51-61-6, 62-31-7; noradrenalin, 1407-84-7, 51-41-2 參考文獻: Sieber, C.C., The elderly patient - who is that? (2007) Internist (Berl.), 48, pp. 1190-1194; Rockwood, K., Song, X., MacKnight, C., A global clinical measure of fitness and frailty in elderly people (2005) CMAJ, 30 (173), pp. 489-495; Ferrucci, L., Guralnik, J.M., Cavazzini, C., The frailty syndrome: a critical issue in geriatric oncology (2003) Crit. Rev. Oncol. Hematol., 46, pp. 127-137; Counsell, S.R., Callahan, C.M., Clark, D.O., Geriatric care management for low-income seniors: a randomized controlled trial (2007) JAMA, 298, pp. 2623-2633; Abbas, S., Booth, M., Major abdominal surgery in octogenarians (2003) N. Z. Med. J., 116 (1172), pp. U402; Huang, T.S., Hu, F.C., Fan, C.W., A simple novel model to predict hospital mortality, surgical site infection, and pneumonia in elderly patients undergoing operation (2010) Dig. Surg., 27 (3), pp. 224-231; Dellinger, R.P., Levy, M.M., Carlet, J.M., Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008 (2008) Crit. Care Med., 36 (1), pp. 296-327; Finfer, S., Bellomo, R., McEvoy, S., Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in intensive care units: analysis of data from the saline versus albumin fluid evaluation (SAFE) study (2006) BMJ, 333 (7577), p. 1044. , SAFE Study Investigators; Mohil, R.S., Bhatnagar, D., Bahadur, L., POSSUM and P-POSSUM for risk-adjusted audit of patients undergoing emergency laparotomy (2004) Br. J. Surg., 91 (4), pp. 500-503; Tran Ba Loc, P., du Montcel, S.T., Duron, J.J., Elderly POSSUM, a dedicated score for prediction of mortality and morbidity after major colorectal surgery in older patients (2010) Br. J. Surg., 97 (3), pp. 396-403; Kroon, H.M., Breslau, P.J., Lardenoye, J.W., Can the incidence of unplanned re-operations be used as an indicator of quality of care in surgery? (2007) Am. J. Med. Qual., 22 (3), pp. 198-202; Louis, D.J., Hsu, A., Brand, M.I., Morbidity and mortality in octogenarians and older undergoing major intestinal surgery (2009) Dis. Colon Rectum, 52 (1), pp. 59-63; Story, D.A., Postoperative complications in elderly patients and their significance for long-term prognosis (2008) Curr. Opin. Anaesthesiol., 21 (3), pp. 375-379; Makary, M.A., Segev, D.L., Pronovost, P.J., Frailty as a predictor of surgical outcomes in older patients (2010) J. Am. Coll. Surg., 210 (6), pp. 901-908; Hyman, N.H., Managing anastomotic leaks from intestinal anastomoses (2009) Surgeon, 7 (1), pp. 31-35; Burger, J.W., Lange, J.F., Halm, J.A., Incisional hernia: early complication of abdominal surgery (2005) World J. Surg., 29 (12), pp. 1608-1613; Ohmann, C., Yang, Q., Hau, T., Wacha, H., Prognostic modelling in peritonitis. Peritonitis Study Group of the Surgical Infection Society Europe (1997) Eur. J. Surg., 163, pp. 53-60; Pacelli, F., Doglietto, G.B., Alfieri, S., Prognosis in intra-abdominal infections. Multivariate analysis on 604 patients (1996) Arch. Surg., 131, pp. 641-645; Robinson, T.N., Eiseman, B., Wallace, J.I., Redefining geriatric preoperative assessment using frailty, disability and co-morbidity (2009) Ann. Surg., 250 (3), pp. 449-455; Chang, T.T., Schecter, W.P., Injury in the elderly and end-of-life decisions (2007) Surg. Clin. North Am., 87 (1), pp. 229-245; Marik, P.E., Management of the critically ill geriatric patient (2006) Crit. Care Med., 34 (9 SUPPL.), pp. S176-S182; Mikkelsen, M.E., Miltiades, A.N., Gaieski, D.F., Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock (2009) Crit. Care Med., 37 (5), pp. 1670-1677; Trzeciak, S., Dellinger, R.P., Chansky, M.E., Serum lactate as a predictor of mortality in patients with infection (2007) Intensive Care Med., 33 (6), pp. 970-977; Arnold, R.C., Shapiro, N.I., Jones, A.E., Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis (2009) Shock, 32 (1), pp. 35-39; Lang, J.D., Figueroa, M., Chumley, P., Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium (2004) Anesthesiology, 100, pp. 51-58; Quinlan, G.J., Margarson, M.P., Mumby, S., Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion (1998) Clin. Sci. (Lond.), 95, pp. 459-465; Daley, J., Khuri, S.F., Henderson, W., Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study (1997) J. Am. Coll. Surg., 185 (4), pp. 328-340; Golub, R., Golub, R.W., Cantu, R., A multivariate analysis of factors contributing to leakage of intestinal anastomoses (1997) J. Am. Coll. Surg., 184 (4), pp. 364-372; Goldwasser, P., Feldman, J., Association of serum albumin and mortality risk (1997) J. Clin. Epidemiol., 50 (6), pp. 693-703; Hennessey, D.B., Burke, J.P., Ni-Dhonochu, T., Preoperative hypoalbuminemia is an independent risk factor for the development of surgical site infection following gastrointestinal surgery: a multi-institutional study (2010) Ann. Surg., 252 (2), pp. 325-329; Sung, J., Bochicchio, G.V., Joshi, M., Admission serum albumin is predictive of outcome in critically ill trauma patients (2004) Am. Surg., 70 (12), pp. 1099-1102; Herrmann, F.R., Safran, C., Levkoff, S.E., Serum albumin level on admission as a predictor of death, length of stay, and readmission (1992) Arch. Intern. Med., 152 (1), pp. 125-130; Nair, A., Pai, D.R., Jagdish, S., Predicting anastomotic disruption after emergent small bowel surgery. Predicting anastomotic disruption after emergent small bowel surgery (2006) Dig. Surg., 23 (1-2), pp. 38-43; Zakrison, T., Nascimento, B.A., Tremblay, L.N., Perioperative vasopressors are associated with an increased risk of gastrointestinal anastomotic leakage (2007) World J. Surg., 31 (8), pp. 1627-1634; Eltarawy, I.G., Etman, Y.M., Zenati, M., Acute mesenteric ischemia: the importance of early surgical consultation (2009) Am. Surg., 75 (3), pp. 212-219; Russell, J.A., Vasopressin in vasodilatory and septic shock (2007) Curr. Opin. Crit. Care, 13 (4), pp. 383-391; Obritsch, M.D., Bestul, D.J., Jung, R., The role of vasopressin in vasodilatory septic shock (2004) Pharmacotherapy, 24 (8), pp. 1050-1063; Lin, M.Y., Rezai, K., Schwartz, D.N., Septic pulmonary emboli and bacteremia associated with deep tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus (2008) J. Clin. Microbiol., 46 (4), pp. 1553-1555; Cook, R.J., Ashton, R.W., Aughenbaugh, G.L., Septic pulmonary embolism: presenting features and clinical course of 14 patients (2005) Chest, 128 (1), pp. 162-166; Abenza-Abildua, M.J., Fuentes-Gimeno, B., Morales-Bastos, C., Stroke due to septic embolism resulting from Aspergillus aortitis in an immunocompetent patient (2009) J. Neurol. Sci., 284 (1-2), pp. 209-210; Ruler, O.V., Mahler, C.W., Boer, K.R., Comparison of on-demand vs planned relaparotomy strategy in patients with severe peritonitis: a randomized trial (2007) JAMA, 298, pp. 865-873; Dubois, M.J., Orellana-Jimenez, C., Melot, C., Albumin administration improves organ function in critically ill hypoalbuminemic patients: a prospective, randomized, controlled, pilot study (2006) Crit. Care Med., 34 (10), pp. 2536-2540; Vincent, J.L., Relevance of albumin in modern critical care medicine (2009) Best Pract. Res. Clin. Anaesthesiol., 23 (2), pp. 183-191; Finfer, S., Myburgh, J., Bellomo, R., Albumin supplementation and organ function (2007) Crit. Care. Med., 35 (3), pp. 987-988
PY - 2014
Y1 - 2014
N2 - Background: As our world ages and the elderly population grows. Surgery on the aged critically ill tend to result in additional morbidity and mortality. We sought to determine early predicting factors that were associated with postoperative leakage and tissue healing deficiency after emergent abdominal surgery in geriatric critically ill patients. Material and method: Retrospectively, geriatric critically ill patients received anticipated, single-stage emergent abdominal surgery via emergency room were enrolled. Patients who received only one definitive surgery during their hospital course were labeled as group A, patients received anticipated one-stage surgery and eventually with postoperative leakage and tissue healing deficiency were labeled as group B. The demographics and parameters were obtained for comparison. Result: There were 45 patients in group A, and 34 patients in group B. The mean age is 77.4 ± 6.1 years in Group A and 76.9 ± 8.5 years in Group B, the mean APACHE score was 20.3 ± 7.5 vs. 21.6 ± 7.7. There were no significances in age, gender, comorbidities, and physiological scores. There were significances in the persistent post-operative use of vasopressors and hypoalbuminemia. The 30-day mortality rate was 0% in group A and 38.2% in group B. Conclusion: Persistent post operative vasopressor use and hypoalbuminemia are associated with higher rate of morbidity and mortality after emergent abdominal surgery in geriatric critically ill patients. Early recognition is essential for proper management. Further studies are required for a better understanding in identifying risk factors. © 2014 Surgical Associates Ltd.
AB - Background: As our world ages and the elderly population grows. Surgery on the aged critically ill tend to result in additional morbidity and mortality. We sought to determine early predicting factors that were associated with postoperative leakage and tissue healing deficiency after emergent abdominal surgery in geriatric critically ill patients. Material and method: Retrospectively, geriatric critically ill patients received anticipated, single-stage emergent abdominal surgery via emergency room were enrolled. Patients who received only one definitive surgery during their hospital course were labeled as group A, patients received anticipated one-stage surgery and eventually with postoperative leakage and tissue healing deficiency were labeled as group B. The demographics and parameters were obtained for comparison. Result: There were 45 patients in group A, and 34 patients in group B. The mean age is 77.4 ± 6.1 years in Group A and 76.9 ± 8.5 years in Group B, the mean APACHE score was 20.3 ± 7.5 vs. 21.6 ± 7.7. There were no significances in age, gender, comorbidities, and physiological scores. There were significances in the persistent post-operative use of vasopressors and hypoalbuminemia. The 30-day mortality rate was 0% in group A and 38.2% in group B. Conclusion: Persistent post operative vasopressor use and hypoalbuminemia are associated with higher rate of morbidity and mortality after emergent abdominal surgery in geriatric critically ill patients. Early recognition is essential for proper management. Further studies are required for a better understanding in identifying risk factors. © 2014 Surgical Associates Ltd.
KW - Geriatric critical ill
KW - Hypoalbuminemia
KW - Vasopressor
KW - adrenalin
KW - dopamine
KW - noradrenalin
KW - abdominal surgery
KW - aged
KW - anastomosis leakage
KW - APACHE
KW - article
KW - controlled study
KW - critically ill patient
KW - emergency ward
KW - evisceration
KW - female
KW - geriatric care
KW - geriatric patient
KW - healing
KW - human
KW - intensive care
KW - intestine perforation
KW - ischemia
KW - laparoscopic surgery
KW - major clinical study
KW - male
KW - morbidity
KW - mortality
KW - operative site bleeding
KW - postoperative complication
KW - postoperative hemorrhage
KW - priority journal
KW - retrospective study
KW - wound dehiscence
KW - abdomen
KW - age
KW - case control study
KW - critical illness
KW - geriatrics
KW - laparotomy
KW - Postoperative Complications
KW - predictive value
KW - procedures
KW - reoperation
KW - surgery
KW - very elderly
KW - wound healing
KW - Abdomen
KW - Age Factors
KW - Aged
KW - Aged, 80 and over
KW - Case-Control Studies
KW - Critical Illness
KW - Female
KW - Geriatrics
KW - Humans
KW - Laparotomy
KW - Male
KW - Predictive Value of Tests
KW - Reoperation
KW - Wound Healing
U2 - 10.1016/j.ijsu.2014.01.016
DO - 10.1016/j.ijsu.2014.01.016
M3 - Article
SN - 1743-9191
VL - 12
SP - 315
EP - 319
JO - International Journal of Surgery
JF - International Journal of Surgery
IS - 4
ER -