TY - JOUR
T1 - Double primary cancers in 2 young sibs, leukemia in another, and dextrocardia in a fourth
AU - Li, Frederick P.
AU - McIntosh, Sue
AU - Peng‐Whang, Jacqueline
PY - 1977/1/1
Y1 - 1977/1/1
N2 - Two brothers developed multiple primary neoplasms in childhood; one had glioblastoma and non‐Hodgkin's lymphoma at age 11 years, and the other brain tumor and acute leukemia at six years. A third brother died with myelogenous leukemia at three years, and a fourth with cyanotic congential heart disease at 11 weeks. Each child aiso had at least one hamartomatous lesion of the skin. The clinical features suggested von Recklinghausen's neurofibromatosis or other inherited cancer syndrome, but laboratory studies identified no markers of susceptibility to familial neoplasia.
AB - Two brothers developed multiple primary neoplasms in childhood; one had glioblastoma and non‐Hodgkin's lymphoma at age 11 years, and the other brain tumor and acute leukemia at six years. A third brother died with myelogenous leukemia at three years, and a fourth with cyanotic congential heart disease at 11 weeks. Each child aiso had at least one hamartomatous lesion of the skin. The clinical features suggested von Recklinghausen's neurofibromatosis or other inherited cancer syndrome, but laboratory studies identified no markers of susceptibility to familial neoplasia.
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U2 - 10.1002/1097-0142(197706)39:6<2633::AID-CNCR2820390649>3.0.CO;2-E
DO - 10.1002/1097-0142(197706)39:6<2633::AID-CNCR2820390649>3.0.CO;2-E
M3 - Article
C2 - 194673
AN - SCOPUS:0017744107
SN - 0008-543X
VL - 39
SP - 2633
EP - 2636
JO - Cancer
JF - Cancer
IS - 6
ER -
