Does peripheral vestibular disorder increase the risk of attempted suicide: A retrospective cohort study

Tzong Hann Yang, Sudha Xirasagar, Yen Fu Cheng, Chin Shyan Chen, Herng Ching Lin

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)


Background: This study aimed to investigate the risk of attempted suicide in the population of patients diagnosed with peripheral vestibular disorders (PVD). Methods: We conducted a retrospective cohort study. We extracted data on patients diagnosed with PVD (72,569 study patients) and a 3:1 ratio of propensity-score matched comparison patients without PVD (217,707 patients) from Taiwan's Longitudinal Health Insurance Database 2010. The claims records of sampled patients were tracked for a one-year period from their index date to identify claims showing a diagnosis of suicide attempt. Cox proportional hazards regression analyses were performed to calculate the one-year hazard ratio (HR) of suicide attempt following the PVD diagnosis among PVD patients relative to comparison patients. Results: Of total 290,276 sampled patients, the rate of attempted suicide was 0.158 per 100 person-years, being 0.460 and 0.057, respectively, among PVD patients and comparison patients. Cox proportional hazard analysis showed that PVD patients had a high relative hazard of suicide attempt (adjusted HR = 7.622, 95 % CI = 6.196–9.376) during one-year follow-up relative to comparison patients. We also found that subcategories of PVD, showed similar adjusted hazard ratios as all PVDs: Meniere's disease (HR = 7.608, 95 % CI = 4.350–13.305), benign paroxysmal positional vertigo (HR = 8.201, 95 % CI = 4.716–14.260), and vestibular neuritis (HR = 9.399, 95 % CI = 5.036–17.544). Limitations: The incidence of suicide attempts could be underestimated in both the study group and comparison group, if the suicide attempt did not cause a medical emergency and the patient did not seek medical assistance. Conclusions: We found a high magnitude of association between PVD and subsequent suicide attempt.
頁(從 - 到)12-16
期刊Journal of Affective Disorders
出版狀態已發佈 - 11月 15 2023

ASJC Scopus subject areas

  • 臨床心理學
  • 精神病學和心理健康


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