TY - JOUR
T1 - Discovery of Natural Veterinary Herbal Medicine Products in Commercial Cow Milk by Using Nontargeted Profiling on LC–ESI–TOF Platform
AU - Wang, San Yuan
AU - Liao, Hsiao Wei
N1 - Funding Information:
Funding was provided by new faculty grants from National Yang-Ming University, junior researcher grants from Taipei Medical University (TMU106-AE1-B35), and the Ministry of Science and Technology of Taiwan (MOST 109-2113-M-010-005-MY3). The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies.
Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2022/4
Y1 - 2022/4
N2 - For centuries, herbal medicines have been used to treat humans and animals. Veterinary medicines are well-regulated; inspectors monitor milk and associated dairy products to screen for unacceptable contaminants. However, few scholars have discussed how the by-products of veterinary herbal medicine can be found in food products. In this paper, we applied nontargeted profiling of the UHPLC–ESI–TOF platform to screen possible by-products originating from veterinary herbal medicine in commercial milk samples. These tentatively identified alkaloids showed high consistency with the plant extract of Holarrhena antidysenterica (L.) Wall. ex A. DC., which indicated the possibility that dairy farmers had used plants from genus Holarrhena as veterinary herbal medicine. This is the first report showing the presence of by-products originating from veterinary herbal medicine in commercial milk. This finding could help authorities to evaluate the use of veterinary herbal medicine in farm animals.
AB - For centuries, herbal medicines have been used to treat humans and animals. Veterinary medicines are well-regulated; inspectors monitor milk and associated dairy products to screen for unacceptable contaminants. However, few scholars have discussed how the by-products of veterinary herbal medicine can be found in food products. In this paper, we applied nontargeted profiling of the UHPLC–ESI–TOF platform to screen possible by-products originating from veterinary herbal medicine in commercial milk samples. These tentatively identified alkaloids showed high consistency with the plant extract of Holarrhena antidysenterica (L.) Wall. ex A. DC., which indicated the possibility that dairy farmers had used plants from genus Holarrhena as veterinary herbal medicine. This is the first report showing the presence of by-products originating from veterinary herbal medicine in commercial milk. This finding could help authorities to evaluate the use of veterinary herbal medicine in farm animals.
KW - Commercial cow milk
KW - Liquid chromatography–electrospray ionization–mass spectrometry
KW - Nontargeted analysis
KW - Veterinary herbal medicine
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U2 - 10.1007/s12161-021-02171-5
DO - 10.1007/s12161-021-02171-5
M3 - Article
AN - SCOPUS:85119068457
SN - 1936-9751
JO - Food Analytical Methods
JF - Food Analytical Methods
ER -