Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry

Y. J. Fan; Chiajui Hsu; Chengpang Liu; Tzuheng Wu; Horn Jiunn Sheen; Shyhfeng Lin

doi:10.1109/MEMSYS.2008.4443625

Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry

Y. J. Fan, Chiajui Hsu, Chengpang Liu, Tzuheng Wu, Horn Jiunn Sheen, Shyhfeng Lin

研究成果: 書貢獻/報告類型 › 會議貢獻

2 引文斯高帕斯（Scopus）

摘要

A novel bio-sensing technique based on Brownian motion change with use of a micro-particle-tracking-velocimetry (micro-PTV) has been successfully developed to measure the antigen-antibody interactions. The rapid interaction between antigen, C-reactive protein (CRP), and the nanobeads conjugated with antibody, anti-CRP, enabled the real-time detection of CRP to be easily carried out. During the binding process of nanobeads to CRP, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. Moreover, higher CRP concentration led to lower Brownian velocity of the nanobead at equilibrium state. Furthermore, the sensitivity was raised when the smaller nanobeads were used.

原文	英語
主出版物標題	MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
頁面	192-195
頁數	4
DOIs	https://doi.org/10.1109/MEMSYS.2008.4443625
出版狀態	已發佈 - 2008
對外發佈	是
事件	21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson - Tucson, AZ, 美国持續時間: 1月 13 2008 → 1月 17 2008

會議

會議	21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
國家/地區	美国
城市	Tucson, AZ
期間	1/13/08 → 1/17/08

ASJC Scopus subject areas

機械工業
電氣與電子工程
控制與系統工程

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10.1109/MEMSYS.2008.4443625

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引用此

Fan, YJ, Hsu, C, Liu, C, Wu, T, Sheen, HJ & Lin, S 2008, Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry. 於 MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems., 4443625, 頁 192-195, 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson, Tucson, AZ, 美国, 1/13/08. https://doi.org/10.1109/MEMSYS.2008.4443625

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title = "Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry",

abstract = "A novel bio-sensing technique based on Brownian motion change with use of a micro-particle-tracking-velocimetry (micro-PTV) has been successfully developed to measure the antigen-antibody interactions. The rapid interaction between antigen, C-reactive protein (CRP), and the nanobeads conjugated with antibody, anti-CRP, enabled the real-time detection of CRP to be easily carried out. During the binding process of nanobeads to CRP, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. Moreover, higher CRP concentration led to lower Brownian velocity of the nanobead at equilibrium state. Furthermore, the sensitivity was raised when the smaller nanobeads were used.",

author = "Fan, {Y. J.} and Chiajui Hsu and Chengpang Liu and Tzuheng Wu and Sheen, {Horn Jiunn} and Shyhfeng Lin",

year = "2008",

doi = "10.1109/MEMSYS.2008.4443625",

language = "English",

isbn = "9781424417933",

pages = "192--195",

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note = "21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson ; Conference date: 13-01-2008 Through 17-01-2008",

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T1 - Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry

AU - Fan, Y. J.

AU - Hsu, Chiajui

AU - Liu, Chengpang

AU - Wu, Tzuheng

AU - Sheen, Horn Jiunn

AU - Lin, Shyhfeng

PY - 2008

Y1 - 2008

N2 - A novel bio-sensing technique based on Brownian motion change with use of a micro-particle-tracking-velocimetry (micro-PTV) has been successfully developed to measure the antigen-antibody interactions. The rapid interaction between antigen, C-reactive protein (CRP), and the nanobeads conjugated with antibody, anti-CRP, enabled the real-time detection of CRP to be easily carried out. During the binding process of nanobeads to CRP, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. Moreover, higher CRP concentration led to lower Brownian velocity of the nanobead at equilibrium state. Furthermore, the sensitivity was raised when the smaller nanobeads were used.

AB - A novel bio-sensing technique based on Brownian motion change with use of a micro-particle-tracking-velocimetry (micro-PTV) has been successfully developed to measure the antigen-antibody interactions. The rapid interaction between antigen, C-reactive protein (CRP), and the nanobeads conjugated with antibody, anti-CRP, enabled the real-time detection of CRP to be easily carried out. During the binding process of nanobeads to CRP, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. Moreover, higher CRP concentration led to lower Brownian velocity of the nanobead at equilibrium state. Furthermore, the sensitivity was raised when the smaller nanobeads were used.

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BT - MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems

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Y2 - 13 January 2008 through 17 January 2008

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Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry

摘要

會議

ASJC Scopus subject areas

存取文件

其它文件與鏈接

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