Deformability of mice erythrocytes measured by oscillatory optical tweezers

Yu Shan Huang, Chia Lun Yeh, Guan Bo Liao, Yi Fan Chen, Ting Fen Tsai, Arthur Chiou

研究成果: 書貢獻/報告類型會議貢獻

1 引文 斯高帕斯(Scopus)


We used one-dimensional oscillatory optical tweezers in a discrete scanning (or jumping) mode to trap and stretch individual mice erythrocytes and measured their deformation as a function of the jumping distance of the oscillatory trapping beam. In general, we observed that the length of the long axis of red blood cells (RBCs) decreased slightly at small jumping distance and then increased after the jumping distance exceeded a threshold value on the order of a few microns, which is consistent with a recent theoretical prediction. The deformability of three types of mice RBCs, namely the wide-type mice (serving as the control group), old mice, and gene knockout mice were measured and compared. Statistical analysis of their deformability reveals that the RBCs of old mice can be distinguished from those of knockout mice even though these two types of mice exhibit many similar aging-like features.
主出版物標題Proceedings of SPIE - The International Society for Optical Engineering
出版狀態已發佈 - 2008
事件Optical Trapping and Optical Micromanipulation V - San Diego, CA, 美国
持續時間: 8月 10 20088月 13 2008


其他Optical Trapping and Optical Micromanipulation V
城市San Diego, CA

ASJC Scopus subject areas

  • 應用數學
  • 電腦科學應用
  • 電氣與電子工程
  • 電子、光磁材料
  • 凝聚態物理學


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