D-Aspartic acid localization during postnatal development of rat adrenal gland

Kumiko Sakai, Hiroshi Homma, Jen Ai Lee, Takeshi Fukushima, Tomofumi Santa, Ken Tashiro, Takeshi Iwatsubo, Kazuhiro Imai

研究成果: 雜誌貢獻文章同行評審

54 引文 斯高帕斯(Scopus)


Developmental changes in cellular localization of D-aspartic acid (D-Asp) were investigated in rat adrenal gland with polyclonal anti-D-Asp antibody. At 1 and 3 weeks of age, immunoreactivity (IR) toward this amino acid was intense in the cytoplasm of cells in the zona fasciculata (ZF) and zona reticularis (ZR) of the adrenal cortex but was less so in the zona glomerulosa (ZG). Conversely at 8 weeks of age, intense IR was observed in the ZG and less in the ZF and ZR. In the adrenal medulla, IR was evident in large clusters of cells which were identified as adrenaline-storing cells. The emergence of D-Asp in specific types of cells at distinct periods of development of rat adrenal gland suggests that this amino acid may have a physiological role in the maturation of the organ.

頁(從 - 到)433-436
期刊Biochemical and Biophysical Research Communications
出版狀態已發佈 - 6月 18 1997

ASJC Scopus subject areas

  • 生物化學
  • 生物物理學
  • 分子生物學


深入研究「D-Aspartic acid localization during postnatal development of rat adrenal gland」主題。共同形成了獨特的指紋。