D-Aspartate localization in the rat pituitary gland and retina

Jen Ai Lee, Hiroshi Homma, Ken Tashiro, Takeshi Iwatsubo, Kazuhiro Imai

研究成果: 雜誌貢獻文章同行評審

57 引文 斯高帕斯(Scopus)


Rat pituitary gland and retina were probed with anti-D-aspartate (D-Asp) antibody previously prepared in this laboratory [Lee et al., Biochem. Biophys. Res. Commun., 231 (1997) 505-508]. D-Asp immunoreactivity (IR) was observed only in the posterior lobe of the pituitary gland of 3-day-old rats, whereas the anterior and posterior lobes were also positive in 3-week and 6- week-old rats, respectively. In the anterior lobe, intense IR was scattered throughout the lobe and the D-Asp-positive cells appeared to be prolactin- containing cells or some other very closely related type of cell. In the retina, D-Asp IR was observed only in the ganglion cell and nerve fiber region of 3-day-old rats. In contrast, during the transient increase in D-Asp levels in 7-day-old rats, D-Asp IR was additionally evident in regions where differentiating bipolar cells had begun to make contact with other types of cells. The functional relevance of D-Asp localization in these tissues is discussed.

頁(從 - 到)193-199
期刊Brain Research
出版狀態已發佈 - 8月 14 1999

ASJC Scopus subject areas

  • 神經科學 (全部)
  • 分子生物學
  • 神經病學(臨床)
  • 發展生物學


深入研究「D-Aspartate localization in the rat pituitary gland and retina」主題。共同形成了獨特的指紋。