Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas

Bahman Anvari, B. S. Tanenbaum, Thomas E. Milner, Wendy Hoffman, Samireh Said, Cheng Jen Chang, Lih Hueh L. Liaw, Sol Kimel, John S.M.D. Nelson

研究成果: 書貢獻/報告類型會議貢獻

6 引文 斯高帕斯(Scopus)

摘要

The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.
原文英語
主出版物標題Proceedings of SPIE - The International Society for Optical Engineering
編輯Frederic Laffitte, Raimund Hibst, Hans-Dieter Reidenbach, Herbert J. Geschwind, Giulio Maira, et.al.
頁面29-37
頁數9
2922
出版狀態已發佈 - 12月 1 1996
對外發佈
事件Laser Applications in Medicine and Dentistry - Vienna, Austria
持續時間: 9月 7 19969月 10 1996

會議

會議Laser Applications in Medicine and Dentistry
城市Vienna, Austria
期間9/7/969/10/96

ASJC Scopus subject areas

  • 電子、光磁材料
  • 凝聚態物理學
  • 電腦科學應用
  • 應用數學
  • 電氣與電子工程

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