Costs and length of stay of drug-related hospital admissions in cancer patients

Yu Ko, Yong Sheng Gwee, Yu Chu Huang, Joen Chiang, Alexandre Chan

研究成果: 雜誌貢獻文章同行評審

11 引文 斯高帕斯(Scopus)


Background Most previous studies of the incidence and economic impact of drug-related hospital admissions were not cancer specific, despite the fact that drug-related problems (DRPs) are of particular concern in oncology. Objective The goals of this study were to assess the economic impact, particularly the length of stay (LOS) and direct medical costs (DMC), of drug-related hospital admissions and the associated factors in cancer patients in Singapore. Methods A prospective study was conducted over a 5-month period in 2 oncology wards at the largest acute tertiary hospital in Singapore. Drug-related admissions were identified from all oncology admissions to these wards, and the demographic, clinical, and cost data of these drug-related admissions were collected. The association between LOS and DMC as well as their associations with age, severity, and preventability of DRPs were examined. A nationwide estimation was made to determine the overall DMC of drug-related hospital admissions among cancer patients. Results A total of 151 drug-related admissions that occurred among 137 cancer patients were identified. The mean DMC (in Singapore dollars [SGD]) and LOS per drug-related admission were SGD $4747 and 6.1 days, respectively. A nationwide extrapolation estimated an annual total DMC of SGD $16.2 million. Longer LOS was found to be correlated with higher DMC (rs = 0.86, P <0.001) and preventable DRPs (P = 0.02). Conclusions Drug-related hospitalization among cancer patients is costly; therefore, more attention is warranted to develop and improve strategies for preventing drug-related morbidity and mortality in cancer patients.

頁(從 - 到)588-592
期刊Clinical Therapeutics
出版狀態已發佈 - 4月 1 2014

ASJC Scopus subject areas

  • 藥理
  • 藥學(醫學)


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