TY - JOUR
T1 - Corrosion resistance and biocompatibility of titanium surface coated with amorphous tantalum pentoxide
AU - Sun, Ying Sui
AU - Chang, Jean Heng
AU - Huang, Her Hsiung
N1 - Funding Information:
This study was partially supported by a research grant from Cheng Hsin General Hospital, Taipei, Taiwan , and Southern Taiwan Bio-Medical Instrument Industry Cluster Project ( AY-22-19-03-100 ), Taiwan. Thanks are also due to Dr. Shih-Hwa Chiou, Taipei Veterans General Hospital, Taiwan, for kindly providing us the human bone marrow mesenchymal stem cells.
PY - 2013/1/15
Y1 - 2013/1/15
N2 - Tantalum pentoxide (Ta2O5) possesses good corrosion resistance and biocompatibility. This study aimed to improve the corrosion resistance and biocompatibility of titanium (Ti) by coating it with an amorphous Ta2O5 surface layer. An amorphous Ta2O 5 layer was prepared on the Ti surface using a simple hydrolysis-condensation process at room temperature. The surface characteristics of the test specimens were analyzed using X-ray photoelectron spectroscopy, glancing angle X-ray diffraction, field emission scanning electron microscopy, and contact angle measurements. The corrosion resistance of the test specimens was evaluated from the potentiodynamic polarization curves and ion release measurements in simulated blood plasma (SBP). The biocompatibility of the test specimens was evaluated in terms of the protein (albumin) adsorption, cell adhesion, and cell growth of human bone marrow mesenchymal stem cells (hBMSCs). The amorphous Ta2O5 layer with a porous micro-/nano-scale topography, which was deposited on the Ti surface using a simple hydrolysis-condensation process, increased the corrosion resistance (i.e., increased the corrosion potential and decreased the anodic current and ion release) of the Ti in the SBP and improved the surface wettability, albumin adsorption, and cell adhesion. We conclude that the presence of an amorphous Ta2O5 layer on the Ti surface increased the corrosion resistance and biocompatibility of Ti.
AB - Tantalum pentoxide (Ta2O5) possesses good corrosion resistance and biocompatibility. This study aimed to improve the corrosion resistance and biocompatibility of titanium (Ti) by coating it with an amorphous Ta2O5 surface layer. An amorphous Ta2O 5 layer was prepared on the Ti surface using a simple hydrolysis-condensation process at room temperature. The surface characteristics of the test specimens were analyzed using X-ray photoelectron spectroscopy, glancing angle X-ray diffraction, field emission scanning electron microscopy, and contact angle measurements. The corrosion resistance of the test specimens was evaluated from the potentiodynamic polarization curves and ion release measurements in simulated blood plasma (SBP). The biocompatibility of the test specimens was evaluated in terms of the protein (albumin) adsorption, cell adhesion, and cell growth of human bone marrow mesenchymal stem cells (hBMSCs). The amorphous Ta2O5 layer with a porous micro-/nano-scale topography, which was deposited on the Ti surface using a simple hydrolysis-condensation process, increased the corrosion resistance (i.e., increased the corrosion potential and decreased the anodic current and ion release) of the Ti in the SBP and improved the surface wettability, albumin adsorption, and cell adhesion. We conclude that the presence of an amorphous Ta2O5 layer on the Ti surface increased the corrosion resistance and biocompatibility of Ti.
KW - Biocompatibility
KW - Corrosion resistance
KW - Tantalum pentoxide
KW - Titanium
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U2 - 10.1016/j.tsf.2012.06.088
DO - 10.1016/j.tsf.2012.06.088
M3 - Article
AN - SCOPUS:84872978286
SN - 0040-6090
VL - 528
SP - 130
EP - 135
JO - Thin Solid Films
JF - Thin Solid Films
ER -