Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

Shang Yeong Kwan; Hann Yeh Shyu; Ji Ho Lin; Tai-Tong Wong; Kai Ping Chang; Chun Hing Yiu

doi:10.1016/j.braindev.2008.03.003

Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

Shang Yeong Kwan, Hann Yeh Shyu, Ji Ho Lin, Tai-Tong Wong, Kai Ping Chang, Chun Hing Yiu

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

摘要

We report the case of a girl with hemimegalencephaly (HME) and Lennox-Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case.

原文	英語
頁（從 - 到）	643-646
頁數	4
期刊	Brain and Development
卷	30
發行號	10
DOIs	https://doi.org/10.1016/j.braindev.2008.03.003
出版狀態	已發佈 - 11月 1 2008
對外發佈	是

ASJC Scopus subject areas

兒科、圍產兒和兒童健康
發展神經科學
神經病學（臨床）

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10.1016/j.braindev.2008.03.003

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abstract = "We report the case of a girl with hemimegalencephaly (HME) and Lennox-Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case.",

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AU - Kwan, Shang Yeong

AU - Shyu, Hann Yeh

AU - Lin, Ji Ho

AU - Wong, Tai-Tong

AU - Chang, Kai Ping

AU - Yiu, Chun Hing

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KW - Epilepsy

KW - Generalized cortical dysplasia

KW - Hemimegalencephaly

KW - Lennox-Gastaut syndrome

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Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

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