TY - JOUR
T1 - Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells
AU - Chan, Err Cheng
AU - Cheng, Chin Sheng
AU - Hsu, Yuan Hsun
PY - 1997
Y1 - 1997
N2 - Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.
AB - Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.
KW - 1,13-dicarboxylic acid
KW - bioconversion
KW - Pseudomonas aeruginosa
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U2 - 10.1016/S0922-338X(97)83575-1
DO - 10.1016/S0922-338X(97)83575-1
M3 - Article
AN - SCOPUS:0030945001
SN - 0922-338X
VL - 83
SP - 157
EP - 160
JO - Journal of Fermentation and Bioengineering
JF - Journal of Fermentation and Bioengineering
IS - 2
ER -