@inbook{ded52d36b32049dbacb10a4520ad41a4,
title = "Computational Analysis of Antibody Paratopes for Antibody Sequences in Antibody Libraries",
abstract = "To ensure the functionalities of the antibodies in phage-displayed synthetic antibody libraries, we use computational method to evaluate the designs of the antibody libraries. The computational methodologies developed in our lab for designing antibody library provide rich information on the function of the designed antibody sequences—adequate antibody designs for a specific antigen type should have predicted paratopes for the antigen type. This computational assessment of the designed antibody sequences helps eliminate non-functional designs before proceeding to construct the library designs in the wet lab. As such, only reasonable antibody designs are constructed for antibody discoveries.",
keywords = "Antibody modeling, Antibody-protein interactions, Functional paratope, Phage display, Rational antibody design, Synthetic antibody library",
author = "Peng, \{Hung Pin\} and Yang, \{An Suei\}",
note = "Publisher Copyright: {\textcopyright} 2023, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2023",
doi = "10.1007/978-1-0716-2609-2\_24",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "437--445",
booktitle = "Methods in Molecular Biology",
}