摘要
Objective: This study determined the clinical efficacy of extracorporeal shockwave therapy and the predictors of its efficacy for knee osteoarthritis. Data Sources: Electronic databases and search engines, namely MEDLINE, PubMed, EMBASE, Cochrane Library Database, Physiotherapy Evidence Database (PEDro), China Academic Journals Full-text Database, and Google Scholar, were searched until 5 March 2019, for randomized controlled trials without restrictions on language and publication year. Review Methods: Eligible trials and extracted data were identified by two independent investigators. The included articles were subjected to a meta-analysis and risk of bias assessment. Outcomes of interest included treatment success rate, pain, and physical function outcomes. A meta-regression analysis was performed to determine the predictors of treatment outcomes following shockwave therapy. Results: We included 50 trials (4844 patients) with a median (range) PEDro score of 6 (5–9). Meta-analyses results revealed an overall significant effect favoring shockwave therapy on the treatment success rate (odds ratio 3.22, 95% confidence interval (CI) 2.21–4.69, P < 0.00001; heterogeneity (I2) = 62%), pain reduction (standardized mean difference (SMD) −2.02, 95% CI −2.38 to −1.67, P < 0.00001; I2 = 95%), and Western Ontario and McMaster Universities Osteoarthritis Index function outcome (SMD −2.71, 95% CI −3.50 to −1.92, P < 0.00001; I2 = 97%). Follow-up duration and energy flux density were independent significant predictors of shockwave efficacy. Conclusion: Shockwave therapy is beneficial for knee osteoarthritis. Shockwave dosage, particularly the energy level and intervention duration, may have different contributions to treatment efficacy.
原文 | 英語 |
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頁(從 - 到) | 1419-1430 |
頁數 | 12 |
期刊 | Clinical Rehabilitation |
卷 | 33 |
發行號 | 9 |
DOIs | |
出版狀態 | 已發佈 - 9月 1 2019 |
ASJC Scopus subject areas
- 物理治療、運動療法和康復
- 復健
指紋
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Supplementary_file_1 – Supplemental material for Clinical efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a systematic review and meta-regression of randomized controlled trials
Chen, H. (Contributor), Liao, C. (Contributor), Huang, S. (Contributor), Tsauo, J. (Contributor) & Liou, T. (Contributor), SAGE Journals, 2019
DOI: 10.25384/sage.8100425.v1, https://doi.org/10.25384%2Fsage.8100425.v1
資料集: Dataset
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Clinical efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a systematic review and meta-regression of randomized controlled trials
Liao, C. (Contributor), Tsauo, J. (Contributor), Liou, T. (Contributor), Chen, H. (Contributor) & Huang, S. (Contributor), Figshare, 2019
DOI: 10.25384/sage.c.4499120.v1, https://sage.figshare.com/collections/Clinical_efficacy_of_extracorporeal_shockwave_therapy_for_knee_osteoarthritis_a_systematic_review_and_meta-regression_of_randomized_controlled_trials/4499120/1
資料集: Dataset