TY - JOUR
T1 - Clinical and pathophysiological correlates of the symptom severity of stress urinary incontinence
AU - Yang, Jenn Ming
AU - Yang, Shwu Huey
AU - Yang, Shu Yu
AU - Yang, Evelyn
AU - Huang, Wen Chen
AU - Tzeng, Chii Ruey
PY - 2010/6
Y1 - 2010/6
N2 - Introduction and hypothesis: The pathophysiology of stress urinary incontinence (SUI) is multifactorial. The aim of this study was to explore the factor determining the symptom severity of SUI. Methods: One hundred twenty-four women with SUI were retrospectively investigated. Clinical data for analyses included demographics, pelvic organ prolapse quantification, SUI severity using a 4-point Likert scale, ultrasound, 1-h pad tests, and urodynamic studies. Data were analyzed using the Spearman's rho test and Kruskal-Wallis test. Results: The symptom severity was not correlated with risk factors of SUI or the morphologic manifestations representing urethral support defect, but was significantly correlated with urine loss on 1-h pad test, Valsalva leak point pressure (VLPP) grading, and maximum urethral closure pressure (MUCP). Women with higher SUI severity had greater urine loss on 1-h pad tests, worse VLPP grading, and lower MUCP. Conclusions: Urethral sphincter function appears to be an important determinant for the symptom severity of SUI.
AB - Introduction and hypothesis: The pathophysiology of stress urinary incontinence (SUI) is multifactorial. The aim of this study was to explore the factor determining the symptom severity of SUI. Methods: One hundred twenty-four women with SUI were retrospectively investigated. Clinical data for analyses included demographics, pelvic organ prolapse quantification, SUI severity using a 4-point Likert scale, ultrasound, 1-h pad tests, and urodynamic studies. Data were analyzed using the Spearman's rho test and Kruskal-Wallis test. Results: The symptom severity was not correlated with risk factors of SUI or the morphologic manifestations representing urethral support defect, but was significantly correlated with urine loss on 1-h pad test, Valsalva leak point pressure (VLPP) grading, and maximum urethral closure pressure (MUCP). Women with higher SUI severity had greater urine loss on 1-h pad tests, worse VLPP grading, and lower MUCP. Conclusions: Urethral sphincter function appears to be an important determinant for the symptom severity of SUI.
KW - Stress urinary incontinence
KW - Symptom severity
KW - Urethral sphincter function
KW - Urethral support
KW - Urodynamic stress incontinence
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U2 - 10.1007/s00192-009-1094-4
DO - 10.1007/s00192-009-1094-4
M3 - Article
C2 - 20135305
AN - SCOPUS:77952976824
SN - 0937-3462
VL - 21
SP - 637
EP - 643
JO - International Urogynecology Journal
JF - International Urogynecology Journal
IS - 6
ER -